Sorensen K V
Biomed Pharmacother. 1984;38(9-10):458-61.
The stability of the somatostatin cells in post-mortem brains obtained 6, 8, 12, 18, 24 and 48 hours after death was examined by use of immunohistochemical technique and compared to the findings in brain material obtained during neurosurgical operations. A considerable decomposition of the somatostatin cells and their processes begins soon after death. The cell bodies dissolve and the cell processes are decomposed into small fragments. The predominant decomposition takes place within the first 6 hours after death as only insignificant further decomposition of the cells and their processes are observed in the preparations obtained 6 hours after death and later. The results demonstrate that it is necessary to obtain the brain material with the shortest possible delay after death, when it is used for post-mortem examinations of the somatostatin cell system in the human brain.
利用免疫组织化学技术检查了死后6、8、12、18、24和48小时获得的尸检大脑中生长抑素细胞的稳定性，并与神经外科手术期间获得的脑材料中的发现进行了比较。死后不久，生长抑素细胞及其突起就开始出现相当程度的分解。细胞体溶解，细胞突起分解成小碎片。主要的分解发生在死后的前6小时内，因为在死后6小时及以后获得的制剂中，仅观察到细胞及其突起的进一步分解不明显。结果表明，当用于人脑生长抑素细胞系统的尸检时，有必要在死后尽可能短的时间内获取脑材料。
