Collin J, Araujo L, Walton J, Lindsell D
Nuffield Department of Surgery, University of Oxford.
Lancet. 1988 Sep 10;2(8611):613-5. doi: 10.1016/s0140-6736(88)90649-6.
824 men aged 65 to 74 were invited for ultrasound screening of the aorta and 426 (51.7%) attended. An abdominal aortic aneurysm was discovered in 23 (5.4%), and in 10 (2.3%) the aneurysm was 4.0 cm or more in diameter. 2 other patients had a common iliac artery aneurysm. The 36 men who had objective evidence of occlusive arterial disease of the lower limbs were twice as likely to be tobacco smokers and accounted for 5 (20%) of the aneurysms discovered. Extension of this screening programme to England and Wales could be expected to identify 52,500 men with an abdominal aortic aneurysm. If elective surgical replacement of the aneurysm were to be accepted by 60% of those with aneurysms 4 cm or more in diameter, 6000 unnecessary deaths from aortic aneurysm rupture could be prevented.
邀请了824名65至74岁的男性进行主动脉超声筛查,426人(51.7%)参加了筛查。发现腹主动脉瘤23例(5.4%),其中直径4.0厘米及以上的动脉瘤10例(2.3%)。另外2例患者患有髂总动脉瘤。有下肢闭塞性动脉疾病客观证据的36名男性吸烟的可能性是其他人的两倍,且占发现的动脉瘤患者的5例(20%)。预计将该筛查项目扩展到英格兰和威尔士,可识别出52,500名腹主动脉瘤患者。如果直径4厘米及以上的动脉瘤患者中有60%接受择期手术置换动脉瘤,那么可预防6000例因主动脉瘤破裂导致的不必要死亡。