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人垂体腺瘤中S-100蛋白的免疫细胞化学研究。

Immunocytochemical study of S-100 protein in human pituitary adenomas.

作者信息

Turpin G, Heshmati H M, Kujas M, Grémain J, Jacque C M, Racadot J

机构信息

Department of Endocrinology, Hôpital de la Pitié, Paris, France.

出版信息

Virchows Arch B Cell Pathol Incl Mol Pathol. 1988;55(2):107-9. doi: 10.1007/BF02896566.

Abstract

The S-100 protein was localized by immunocytochemistry in 70 pituitary tumors including 30 prolactin, 16 growth hormone, two corticotropin and 22 non-functioning adenomas. Positive immunostaining was observed in only one case (prolactin adenoma). It is concluded that in functioning and non-functioning pituitary tumors there is no particular involvement of S-100 protein-containing cells, at least under the conditions of this study.

摘要

通过免疫细胞化学方法对70例垂体瘤进行S-100蛋白定位,其中包括30例催乳素瘤、16例生长激素瘤、2例促肾上腺皮质激素瘤和22例无功能腺瘤。仅在1例(催乳素腺瘤)中观察到阳性免疫染色。得出的结论是,在功能性和无功能性垂体瘤中,至少在本研究条件下,含S-100蛋白的细胞没有特别的参与。

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