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孕期大鼠胎盘鸟氨酸脱羧酶和转谷氨酰胺酶活性

Ornithine decarboxylase and transglutaminase activities in rat placenta during pregnancy.

作者信息

Pinturo R, Campisi A, Sorrenti V, Di Giacomo C, Gambera G, Castorina C, Vanella A

机构信息

Institute of Biochemistry, University di Catania, Italy.

出版信息

Acta Eur Fertil. 1988 Jan-Feb;19(1):45-8.

PMID:2901183
Abstract

Ornithine decarboxylase (L-Orbithine carboxylase, E.C. 4.1.1.17) and transglutaminase (R-glutaminylpeptide: amine gamma-glutamyltransferase, E.C. 2.3.2.1.13), enzymes implicated in the regulation of growth processes, were studied in rat placenta during pregnancy; the specific activity of TGase increased from the 15th day until the 21st day of pregnancy while no significant difference of ODC activity was observed; moreover, the ODCase/TGase ratio decreased significantly in rat term placenta.

摘要

鸟氨酸脱羧酶(L-鸟氨酸羧化酶,E.C. 4.1.1.17)和转谷氨酰胺酶(R-谷氨酰胺基肽:胺γ-谷氨酰转移酶,E.C. 2.3.2.1.13)是参与生长过程调节的酶,在大鼠孕期胎盘内进行了研究;转谷氨酰胺酶的比活性从妊娠第15天到第21天增加,而鸟氨酸脱羧酶活性未观察到显著差异;此外,足月大鼠胎盘内鸟氨酸脱羧酶/转谷氨酰胺酶的比值显著降低。

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