Pinturo R, Campisi A, Sorrenti V, Di Giacomo C, Gambera G, Castorina C, Vanella A
Institute of Biochemistry, University di Catania, Italy.
Acta Eur Fertil. 1988 Jan-Feb;19(1):45-8.
Ornithine decarboxylase (L-Orbithine carboxylase, E.C. 4.1.1.17) and transglutaminase (R-glutaminylpeptide: amine gamma-glutamyltransferase, E.C. 2.3.2.1.13), enzymes implicated in the regulation of growth processes, were studied in rat placenta during pregnancy; the specific activity of TGase increased from the 15th day until the 21st day of pregnancy while no significant difference of ODC activity was observed; moreover, the ODCase/TGase ratio decreased significantly in rat term placenta.
鸟氨酸脱羧酶(L-鸟氨酸羧化酶,E.C. 4.1.1.17)和转谷氨酰胺酶(R-谷氨酰胺基肽:胺γ-谷氨酰转移酶,E.C. 2.3.2.1.13)是参与生长过程调节的酶,在大鼠孕期胎盘内进行了研究;转谷氨酰胺酶的比活性从妊娠第15天到第21天增加,而鸟氨酸脱羧酶活性未观察到显著差异;此外,足月大鼠胎盘内鸟氨酸脱羧酶/转谷氨酰胺酶的比值显著降低。