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胚胎期雏鸡肠道葡萄糖主动转运的发育。甲状腺素和氢化可的松的影响。

Development of glucose active transport in embryonic chick intestine. Influence of thyroxine and hydrocortisone.

作者信息

Black B L

机构信息

Department of Zoology, North Carolina State University, Raleigh 27695-7617.

出版信息

Comp Biochem Physiol A Comp Physiol. 1988;90(3):379-86. doi: 10.1016/0300-9629(88)90205-8.

DOI:10.1016/0300-9629(88)90205-8
PMID:2901307
Abstract
  1. Glucose active transport is detectable in 12-day-old embryonic chick duodenum and increases at least 11-fold after 4 days of postnatal life. 2. Glucose active transport develops at the in vivo rate in 72-hr cultures of 14-day embryonic duodenum. 3. In the presence of either 1 nM thyroxine or 1 microM hydrocortisone in vitro, glucose active transport reaches levels approximately 200% of control values (equivalent to 18-19 day levels in vivo). 4. Thyroxine and hydrocortisone act by different mechanisms based on their antagonistic interaction and differences in time course of action, requirement for protein synthesis and modulation by extracellular calcium.
摘要
  1. 葡萄糖主动转运在12日龄鸡胚十二指肠中可检测到,出生后4天内至少增加11倍。2. 在14日龄胚胎十二指肠的72小时培养物中,葡萄糖主动转运以体内速率发育。3. 在体外存在1 nM甲状腺素或1 microM氢化可的松的情况下,葡萄糖主动转运达到对照值的约200%(相当于体内18 - 19日龄水平)。4. 基于甲状腺素和氢化可的松的拮抗相互作用、作用时间进程差异、对蛋白质合成的需求以及细胞外钙的调节,它们通过不同机制起作用。

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Development of glucose active transport in embryonic chick intestine. Influence of thyroxine and hydrocortisone.胚胎期雏鸡肠道葡萄糖主动转运的发育。甲状腺素和氢化可的松的影响。
Comp Biochem Physiol A Comp Physiol. 1988;90(3):379-86. doi: 10.1016/0300-9629(88)90205-8.
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