奥沙拉嗪作为柳氮磺胺吡啶诱导的嗜酸性粒细胞性肺炎患者的替代疗法。
Olsalazine as an alternative therapy in a patient with sulfasalazine-induced eosinophilic pneumonia.
作者信息
Scherpenisse J, van der Valk P D, van den Bosch J M, van Hees P A, Nadorp J H
机构信息
Department of Gastroenterology, St. Antonius Hospital, Nieuwegein, The Netherlands.
出版信息
J Clin Gastroenterol. 1988 Apr;10(2):218-20. doi: 10.1097/00004836-198804000-00024.
Abstract
A man with Crohn's colitis developed eosinophilic pneumonia after treatment with sulfasalazine. Challenge with sulfapyridine revealed that this component of sulfasalazine was the likely causative agent. Treatment with olsalazine, a 5-aminosalicylic acid compound (disodium-azodisalicylate), was well tolerated without recurrence of pulmonary symptoms.
摘要
一名患有克罗恩病结肠炎的男子在使用柳氮磺胺吡啶治疗后发生嗜酸性粒细胞性肺炎。对磺胺吡啶进行激发试验显示，柳氮磺胺吡啶的这一成分可能是致病因素。使用奥沙拉嗪（一种5-氨基水杨酸化合物，偶氮双水杨酸二钠）治疗，耐受性良好，肺部症状未复发。
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