Lundeberg T, Kjartansson J, Samuelsson U
Department of Physiology II, Karolinska Institute, Stockholm, Sweden.
Lancet. 1988 Sep 24;2(8613):712-4. doi: 10.1016/s0140-6736(88)90187-0.
Blood circulation was measured by laser doppler flowmetry in fasciocutaneous flaps of 24 patients who underwent reconstructive surgery for mammary carcinoma. 19 of the 24 patients had clinical signs of deficient circulation in the flaps. 14 patients were treated with electrical nerve stimulation (ENS) and 10 with placebo-ENS. Varying degrees of necrosis developed in 8 of the 10 patients who received placebo stimulation but in none of those treated with ENS. In the 5 patients with good capillary refilling and no signs of stasis or oedema before treatment, only minor increases in blood flow occurred after ENS.
采用激光多普勒血流仪对24例因乳腺癌接受重建手术患者的筋膜皮瓣进行血液循环测量。24例患者中有19例皮瓣出现血液循环不足的临床体征。14例患者接受电神经刺激(ENS)治疗,10例接受安慰剂电神经刺激治疗。接受安慰剂刺激的10例患者中有8例出现不同程度的坏死,而接受ENS治疗的患者均未出现坏死。在治疗前毛细血管再充盈良好且无淤血或水肿迹象的5例患者中,ENS治疗后血流量仅有轻微增加。