Li Yiming, Dong Weiwei, Wang Min, Xu Ning
*Department of Dermatology and Venereology, Huaxi Hospital, Chengdu, China; †Department of Dermatology, Sichuan FreSkin Hospital, Chengdu, China; ‡Department of Dermatology, Xian FreSkin Hospital, Xian, China; §Department of Dermatology, Chongqing FreSkin Hospital, Chongqing, China.
Dermatol Surg. 2017 Dec;43 Suppl 3:S329-S335. doi: 10.1097/DSS.0000000000001349.
Vibration has been proved to be effective to reduce pain during facial cosmetic injections, but it has not been studied in Chinese patients.
To investigate the efficacy and safety of vibration for pain reduction associated with cosmetic botulinum toxin A (BTX-A) injections in Chinese patients.
In this prospective, randomized, split-face and right-left, self-controlled study, 53 patients received BTX-A injections for rhytid reduction, lower face, shoulder, and leg reshaping. Injections were given in a split-face and right-left design randomly assigned. A vibration stimulus was coadministered with BTX-A injections on one side, whereas the other side received BTX-A injections only. Patients completed a questionnaire immediately after treatment and were followed up 2 weeks later. A visual analog scale of pain sensation was statistically analyzed.
The patients experienced both clinically and statistically significant pain reduction when a vibration was coadministered with injections. Patients reported less pain on the treated side compared with the control side. Overall, 75% of patients preferred to receive vibration with their next treatment. No adverse events were reported.
Vibration is an effective and safe way to reduce pain during cosmetic BTX-A injections and may have applications in other cosmetic procedures.
振动已被证明在面部美容注射过程中能有效减轻疼痛，但尚未在中国患者中进行研究。
探讨振动对中国患者在美容用A型肉毒毒素（BTX-A）注射时减轻疼痛的有效性和安全性。
在这项前瞻性、随机、半脸和左右自身对照研究中，53例患者接受BTX-A注射以减少皱纹、重塑下脸、肩部和腿部。注射采用随机分配的半脸和左右设计。一侧在注射BTX-A时同时给予振动刺激，而另一侧仅接受BTX-A注射。患者在治疗后立即完成一份问卷，并在2周后进行随访。对疼痛感觉的视觉模拟量表进行统计学分析。
当注射时同时给予振动刺激，患者在临床和统计学上均经历了显著的疼痛减轻。与对照侧相比，患者报告治疗侧疼痛较轻。总体而言，75%的患者更愿意在下次治疗时接受振动刺激。未报告不良事件。
振动是美容用BTX-A注射过程中减轻疼痛的一种有效且安全的方法，可能在其他美容手术中也有应用。
