Department of Cardiology, The Jikei University School of Medicine, 3-25-8, Nishi-shinbashi, Minato-ku, Tokyo 105-8461, Japan.
Europace. 2018 Jun 1;20(6):943-948. doi: 10.1093/europace/eux129.
Establishment of pulmonary vein isolation (PVI) during cryoballoon (CB) ablation is generally confirmed by use of an octapolar inner-lumen mapping catheter (Achieve®). The aim of this study is to evaluate the residual PV potential (PVP) using the conventional circular catheter after CB-PVI.
A total of 105 consecutive patients (418 PVs) with paroxysmal AF who underwent the initial CB-PVI were prospectively included in this study. Of those, 305 (73%) PVs with real-time recordings of PVP elimination by Achieve® catheter during successful PVI were included. After isolation of all 4 PVs, PV antral remapping by conventional circular mapping catheter was performed. After CB-PVI, residual PVP was detected in 4.3% (13/305) of PVs (1.2% of left-superior PV, 2.5% of left-inferior PV, none of right-superior PV, and 20% of right-inferior PV). Almost 60% of residual PV potential was located around the bottom portion of the right-inferior PV. In PVs with residual potential, PV trunk was shorter (12.7 ± 5.7 mm vs. 18.7 ± 7.9, P = 0.001), minimal balloon temperature was higher (-46.6 ± 5.9 °C vs. -50.9 ± 8.2, P = 0.02), and balloon warming time was shorter (35.6 ± 17.8 s vs. 50.0 ± 22.8, P = 0.006) than those without. All residual potentials were eliminated by additional touch up ablation. After the initial ablation procedure, 1-year AF-free rate was 79.5%.
PV remapping after CB-PVI revealed residual antral PVP in 4.3% of PVs and in 20% of RIPVs in particular. The Achieve® catheter sometimes fails to detect complete PV antral isolation.
在冷冻球囊(CB)消融过程中建立肺静脉隔离(PVI)通常通过使用八极内腔标测导管(Achieve®)来确认。本研究旨在使用常规的圆形导管评估 CB-PVI 后的残余 PV 电位(PVP)。
本研究前瞻性纳入了 105 例接受初始 CB-PVI 的阵发性 AF 连续患者(418 条 PV)。其中,305 条(73%)PV 成功 PVI 期间使用 Achieve®导管实时记录 PVP 消除的 PV 被纳入研究。在隔离所有 4 条 PV 后,使用常规圆形标测导管对 PV 窦进行重新标测。CB-PVI 后,在 305 条(4.3%)PV 中检测到残余 PVP(左上 PV 为 1.2%,左下 PV 为 2.5%,右上 PV 为 0%,右下 PV 为 20%)。几乎 60%的残余 PV 电位位于右下 PV 的底部附近。在有残余电位的 PV 中,PV 干较短(12.7±5.7mm 比 18.7±7.9mm,P=0.001),最小球囊温度较高(-46.6±5.9°C 比-50.9±8.2°C,P=0.02),球囊升温时间较短(35.6±17.8s 比 50.0±22.8s,P=0.006)。所有残余电位均通过额外的触诊消融消除。初始消融术后 1 年 AF 无复发率为 79.5%。
CB-PVI 后 PV 重新标测显示,4.3%的 PV 和特别是 20%的右下 PV 存在残余窦房结 PVP。Achieve®导管有时无法检测到完全的 PV 窦房结隔离。