人类嗜T淋巴细胞病毒I型相关脊髓病（HAM）患者血清中针对EB病毒的抗体滴度升高。
Elevated serum antibody titers to Epstein-Barr virus in HTLV-I-associated myelopathy (HAM).
作者信息
Itoyama Y, Minato S, Goto I, Okochi K, Yamamoto N
机构信息
Department of Neurology, Kyushu University, Fukuoka, Japan.
出版信息
Neurology. 1988 Oct;38(10):1650-3. doi: 10.1212/wnl.38.10.1650.
We studied the serum antibody titers to Epstein-Barr virus (EBV) in 11 patients with HTLV-I-associated myelopathy (HAM). HAM patients showed significant increases in IgG antibodies to EBV-capsid antigen (VCA) and -early antigen (EA) and in VCA-specific IgA compared with 25 seronegative subjects. However, there were no significant differences in antibodies to EBV-nuclear antigen (EBNA) or to other viruses between the two groups. In HAM patients, altered antibody responses occurred specifically to EBV-associated antigens, not to other viruses.
我们研究了11例成人T细胞白血病病毒I型相关脊髓病（HAM）患者的血清抗Epstein-Barr病毒（EBV）抗体滴度。与25名血清阴性受试者相比，HAM患者的EBV衣壳抗原（VCA）和早期抗原（EA）的IgG抗体以及VCA特异性IgA显著增加。然而，两组之间EBV核抗原（EBNA）或其他病毒的抗体没有显著差异。在HAM患者中，抗体反应的改变是特异性针对EBV相关抗原的，而非其他病毒。
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