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血液透析患者心律失常症状的发生率及植入式心脏监测器的可接受性

Frequency of arrhythmia symptoms and acceptability of implantable cardiac monitors in Hemodialysis patients.

作者信息

El Hage Naya, Jaar Bernard G, Cheng Alan, Knight Chloe, Blasco-Colmenares Elena, Gimenez Luis, Guallar Eliseo, Shafi Tariq

机构信息

Western Pennsylvania Hospital, Pittsburgh, PA, USA.

Division of Nephrology, Department of Medicine, Johns Hopkins University School of Medicine, 301 Mason Lord Drive, Suite 2500, Baltimore, MD, 21224-2780, USA.

出版信息

BMC Nephrol. 2017 Oct 10;18(1):309. doi: 10.1186/s12882-017-0740-1.

Abstract

BACKGROUND

Arrhythmia-related complications and sudden death are common in dialysis patients. However, routine cardiac monitoring has so far not been feasible. Miniaturization of implantable cardiac monitors offers a new paradigm for detection and management of arrhythmias in dialysis patients. The goal of our study was to determine the frequency of arrhythmia-related symptoms in hemodialysis patients and to assess their willingness to undergo implantation of a cardiac monitor.

METHODS

We conducted a survey of in-center hemodialysis patients at a hemodialysis clinic in Baltimore, Maryland. We assessed the frequency of arrhythmia-related symptoms and willingness to undergo placement of an implantable cardiac monitor (LINQ, Medtronic Inc.).

RESULTS

Forty six patients completed the survey. The mean age of the survey respondents was 59 years and 65% were male. Symptoms were common with 74% (n = 34) of participants reporting at least one arrhythmia-related symptom and many [22% (n = 10)] had all 3 symptoms. Among the patients with symptoms, 57% (n = 26) reported "heart skipping beats, flopping in chest or beating very hard," 61% (n = 28) reported "heart racing (palpitations)," and 37% (n = 17) reported feeling that they "passed out or almost passed out." The majority of the patients felt that the timing of the symptoms was unrelated to dialysis treatments. The acceptability of the monitoring device implantation was high, with 59% (n = 20) of patients with symptoms and 50% (n = 6) of patients without symptoms willing to consider it. The main reason for not considering the device was not wanting to have an implanted device.

CONCLUSION

The prevalence of arrhythmia-related symptoms is high in hemodialysis patients and the majority would consider an implantable cardiac monitor if recommended by their physicians. Routine implantation of cardiac monitoring devices to manage arrhythmias in dialysis patients may be feasible and will provide further insights on the leading causes of morbidity and mortality in dialysis patients.

摘要

背景

心律失常相关并发症和猝死在透析患者中很常见。然而,常规心脏监测目前尚不可行。可植入心脏监测器的小型化为透析患者心律失常的检测和管理提供了一种新范例。我们研究的目的是确定血液透析患者心律失常相关症状的发生率,并评估他们接受植入心脏监测器的意愿。

方法

我们对马里兰州巴尔的摩一家血液透析诊所的中心血液透析患者进行了一项调查。我们评估了心律失常相关症状的发生率以及接受植入式心脏监测器(美敦力公司的LINQ)的意愿。

结果

46名患者完成了调查。调查对象的平均年龄为59岁,65%为男性。症状很常见,74%(n = 34)的参与者报告至少有一种心律失常相关症状,许多人[22%(n = 10)]有所有三种症状。在有症状的患者中,57%(n = 26)报告“心跳漏跳、胸部跳动或跳动剧烈”,61%(n = 28)报告“心跳加速(心悸)”,37%(n = 17)报告感觉自己“昏厥或几乎昏厥”。大多数患者认为症状出现的时间与透析治疗无关。监测设备植入的可接受性很高,有症状患者中的59%(n = 20)和无症状患者中的50%(n = 6)愿意考虑。不考虑该设备的主要原因是不想植入设备。

结论

血液透析患者中心律失常相关症状的患病率很高,如果医生推荐,大多数人会考虑植入式心脏监测器。常规植入心脏监测设备以管理透析患者的心律失常可能是可行的,并将为透析患者发病和死亡的主要原因提供进一步的见解。

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本文引用的文献

1
Sudden Cardiac Death Among Hemodialysis Patients.血液透析患者中的心脏性猝死
Am J Kidney Dis. 2017 May;69(5):684-695. doi: 10.1053/j.ajkd.2016.12.006. Epub 2017 Feb 17.

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