Mahmood Humera, Fatima Hadia, Faheem Mohammad
Department of Oncology, Atomic Energy Cancer Hospital, Nori, Islamabad.
J Coll Physicians Surg Pak. 2017 Sep;27(9):579-581.
Mammary analogue secretory carcinoma (MASC) is a rare salivary gland malignancy that exhibits resemblance with secretory carcinoma of the breast (SC) due to the presence of ETV6-NTRK3 gene fusion, formerly classified as acinic cell carcinoma. It is a slowly growing painless tumor that exhibits wide range of clinical behavior. This tumor typically affects middle aged people. Less than 100 such cases have been reported in the literature so far with only 8 case reports of patients less than 19 years of age. Very little is known about the clinical management of such cases. We hereby report a case of 15-year boy who had been managed for MASC of left parotid gland with exision.
乳腺样分泌性癌（MASC）是一种罕见的唾液腺恶性肿瘤，由于存在ETV6-NTRK3基因融合，它与乳腺分泌性癌（SC）相似，以前被归类为腺泡细胞癌。它是一种生长缓慢的无痛性肿瘤，表现出广泛的临床行为。这种肿瘤通常影响中年人。迄今为止，文献中报道的此类病例不到100例，其中年龄小于19岁的患者仅有8例病例报告。对此类病例的临床管理知之甚少。我们在此报告一例15岁男孩，其左侧腮腺的MASC接受了切除治疗。
