von Dorsche H H, Fält K, Hahn H J, Reiher H
Institut für Anatomie des Bereiches Medizin der Ernst-Moritz-Arndt-Universität, Greifswald.
Acta Histochem Suppl. 1988;35:137-43.
The investigations are carried out in 19 human fetal pancreases. The detection of the 4 islet hormones insulin, glucagon, somatostatin and PP ist carried out in PAP-technique. The parts of these 4 types of islet cells are estimated quantitatively. In the 10th to 15th week of development insulin-producing B-cells are present. Moreover glucagon-, somatostatin- and PP-cells in the islet organ are present. In the group of 16th to 20th week of gestation insulin-, glucagon- and somatostatin-cells are increased compared to the first group. PP-cells are not altered. The increase of 3 types of islet cells is a result of fetal development.
对19个人类胎儿胰腺进行了研究。采用PAP技术检测4种胰岛激素胰岛素、胰高血糖素、生长抑素和PP。对这4种胰岛细胞的部分进行了定量估计。在发育的第10至15周，存在产生胰岛素的B细胞。此外，胰岛器官中还存在胰高血糖素、生长抑素和PP细胞。在妊娠第16至20周的组中，与第一组相比，胰岛素、胰高血糖素和生长抑素细胞增加。PP细胞没有变化。3种胰岛细胞的增加是胎儿发育的结果。
