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严重创伤后的生存情况及与健康相关的生活质量——一项15年的随访研究。

Survival and health related quality of life after severe trauma - a 15 years follow up study.

作者信息

Wad Morten S, Laursen Thomas, Fruergaard Sidsel, Morgen Søren Schmidt, Dahl Benny

机构信息

Spine Unit, Department of Orthopedic Surgery, Rigshospitalet, University of Copenhagen, Denmark.

Spine Unit, Department of Orthopedic Surgery, Rigshospitalet, University of Copenhagen, Denmark.

出版信息

Injury. 2018 Feb;49(2):191-194. doi: 10.1016/j.injury.2017.10.001. Epub 2017 Oct 5.

DOI:10.1016/j.injury.2017.10.001
PMID:29017766
Abstract

INTRODUCTION

As the primary treatment of patients with severe trauma continues to improve, increasing interest has been directed towards long-term survival and Health Related Quality of Life (HRQoL). In trauma patients, there are few studies describing long-term outcome using tools specifically directed at HRQoL.

HYPOTHESIS

HRQoL measured with EQ-5D is significantly reduced compared to the Danish norm score 15 years after severe injury.

MATERIALS AND METHODS

All patients more than 18 years of age, admitted to a level 1 trauma center from March 1996 to September 1997 were prospectively included and scored with Injury Severity Score (ISS). Survival status was recorded in May 2012 and EQ-5D questionnaires were sent out.

RESULTS

95 of the original 154 trauma patients were eligible for participation. The response rate was 66%. The average EQ-5D index score in the trauma population was significantly reduced compared to the index score in the Danish norm population (P=0.00, one-sample t-test). In addition, ISS is associated with HRQoL and ISS≥16 predicts poorer HRQoL.

CONCLUSION

EQ-5D is significantly reduced 15years after severe trauma High ISS was associated with low HRQoL. Knowledge of the distribution and predictors of long-term disability can be used to develop more efficient prevention policies and to improve trauma care in general.

摘要

引言

随着严重创伤患者的主要治疗方法不断改进,人们越来越关注长期生存率和健康相关生活质量(HRQoL)。在创伤患者中,很少有研究使用专门针对HRQoL的工具来描述长期预后。

假设

与丹麦正常评分相比,严重受伤15年后用EQ-5D测量的HRQoL显著降低。

材料与方法

前瞻性纳入1996年3月至1997年9月入住一级创伤中心的所有18岁以上患者,并用损伤严重度评分(ISS)进行评分。2012年5月记录生存状态,并发放EQ-5D问卷。

结果

154名创伤患者中的95名符合参与条件。应答率为66%。与丹麦正常人群的指数评分相比,创伤人群的平均EQ-5D指数评分显著降低(P=0.00,单样本t检验)。此外,ISS与HRQoL相关,ISS≥16预示着较差的HRQoL。

结论

严重创伤15年后EQ-5D显著降低。高ISS与低HRQoL相关。了解长期残疾的分布和预测因素可用于制定更有效的预防政策,并总体上改善创伤护理。

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