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多学科治疗环境下治疗的糖尿病足伤口患者的非计划性 30 天再入院。

Unplanned 30-day readmission in patients with diabetic foot wounds treated in a multidisciplinary setting.

机构信息

Department of Surgery, The Johns Hopkins Hospital, Baltimore, Md.

Diabetic Foot and Wound Service, The Johns Hopkins Hospital, Baltimore, Md; Division of Vascular Surgery and Endovascular Therapy, The Johns Hopkins Hospital, Baltimore, Md.

出版信息

J Vasc Surg. 2018 Mar;67(3):876-886. doi: 10.1016/j.jvs.2017.07.131. Epub 2017 Oct 7.

Abstract

OBJECTIVE

Readmission rates are known to be high for vascular surgery patients in general, but there are limited data describing the risk of surgical and nonsurgical readmission among patients with diabetic foot ulcers (DFUs). Our aim was to identify factors associated with unplanned readmission in DFU patients treated in a multidisciplinary setting.

METHODS

We studied a single-center cohort of patients enrolled in a multidisciplinary diabetic foot service (July 2012-June 2017). Readmissions were stratified by planned vs unplanned and related vs unrelated to the wound and vascular status. Predictors of unplanned 30-day readmission were examined with univariable and multivariable logistic regression models including all covariates with P ≤ .10.

RESULTS

There were 460 admissions in 206 patients during the study period, including 99 total readmissions (21.5%). Readmissions were categorized as planned (n = 18 [18.2%]) or unplanned (n = 81 [81.8%]) and as related (n = 67 [67.7%]) or unrelated (n = 32 [32.3%]) to the wound and vascular status. The most frequent reasons for unplanned 30-day readmission were deterioration of the foot wound (41%), vascular complications (15%), gastrointestinal complications (10%), cardiac complications (8%), and acute kidney injury (8%). The average length of stay for the initial admission was 9.0 ± 7.1 days, whereas the average unplanned readmission length of stay was 8.6 ± 9.1 days (P = .38). On univariable analysis, hypertension (odds ratio [OR], 2.80; 95% confidence interval [CI], 1.19-6.59), peripheral arterial disease (OR, 1.80; 95% CI, 1.09-2.99), and exposure to an open vascular operation (OR, 2.64; 95% CI, 1.34-5.17) were associated with a higher risk of 30-day unplanned readmission (P ≤ .02). Private, military, or self-pay insurance was protective (OR, 0.52; 95% CI, 0.28-0.97). Wound duration, location, and Wound, Ischemia, and foot Infection (WIfI) classification were not associated with readmission (P ≥ .22). After risk adjustment, only hypertension (OR, 2.80; 95% CI, 1.19-6.59) and current smoking (OR, 1.95; 95% CI, 1.02-3.73) were independently associated with 30-day unplanned readmission, but the predictive accuracy of the model was weak (C statistic = 0.69).

CONCLUSIONS

We found a 17% unplanned 30-day readmission rate in this prospective cohort of DFU patients enrolled in a multidisciplinary diabetic foot service. Only current smoking and hypertension were independent predictors of readmission after risk adjustment. These findings suggest that implementation of a smoking cessation program may be beneficial to reduce unplanned readmissions in DFU patients. They also highlight the complexity involved in achieving comprehensive DFU care and the unpredictability of readmissions in this unique population of patients.

摘要

目的

血管外科患者的再入院率通常较高,但有关糖尿病足溃疡(DFU)患者手术和非手术再入院风险的数据有限。我们的目的是确定在多学科环境中治疗 DFU 患者时与计划性和非计划性再入院相关的因素。

方法

我们研究了一个单中心队列的患者,这些患者被纳入多学科糖尿病足服务中(2012 年 7 月至 2017 年 6 月)。根据计划与非计划以及与伤口和血管状况的相关与非相关对再入院进行分层。使用单变量和多变量逻辑回归模型检查了 30 天非计划性再入院的预测因素,包括所有 P ≤.10 的协变量。

结果

在研究期间,206 名患者中有 460 次入院,包括 99 次总再入院(21.5%)。再入院分为计划(n=18[18.2%])和非计划(n=81[81.8%]),以及与伤口和血管状况相关(n=67[67.7%])和非相关(n=32[32.3%])。30 天非计划性再入院的最常见原因是足部伤口恶化(41%)、血管并发症(15%)、胃肠道并发症(10%)、心脏并发症(8%)和急性肾损伤(8%)。初次入院的平均住院时间为 9.0±7.1 天,而非计划性再入院的平均住院时间为 8.6±9.1 天(P=.38)。单变量分析显示,高血压(比值比[OR],2.80;95%置信区间[CI],1.19-6.59)、外周动脉疾病(OR,1.80;95%CI,1.09-2.99)和暴露于开放性血管手术(OR,2.64;95%CI,1.34-5.17)与 30 天非计划性再入院风险增加相关(P ≤.02)。私人、军人或自付保险具有保护作用(OR,0.52;95%CI,0.28-0.97)。伤口持续时间、位置和伤口、缺血和足部感染(WIfI)分类与再入院无关(P≥.22)。风险调整后,只有高血压(OR,2.80;95%CI,1.19-6.59)和当前吸烟(OR,1.95;95%CI,1.02-3.73)与 30 天非计划性再入院独立相关,但模型的预测准确性较弱(C 统计量=0.69)。

结论

我们在多学科糖尿病足服务中纳入的前瞻性 DFU 患者队列中发现了 17%的 30 天非计划性再入院率。只有当前吸烟和高血压是再入院的独立预测因素。这些发现表明,实施戒烟计划可能有助于减少 DFU 患者的非计划性再入院。它们还强调了在这个独特的患者群体中实现全面 DFU 护理的复杂性和再入院的不可预测性。

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