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Growth inhibition and induction of phenotypic alterations in MCF-7 breast cancer cells by an IMP dehydrogenase inhibitor.

作者信息

Sidi Y, Panet C, Wasserman L, Cyjon A, Novogrodsky A, Nordenberg J

机构信息

Rogoff Medical Research Institute, Department of Medicine D, Beilinson Medical Center, Petah Tikva, Israel.

出版信息

Br J Cancer. 1988 Jul;58(1):61-3. doi: 10.1038/bjc.1988.162.

DOI:10.1038/bjc.1988.162
PMID:2901850
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2246497/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bcf5/2246497/0c54717781d1/brjcancer00129-0076-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bcf5/2246497/0c54717781d1/brjcancer00129-0076-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bcf5/2246497/0c54717781d1/brjcancer00129-0076-a.jpg

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Growth inhibition and induction of phenotypic alterations in MCF-7 breast cancer cells by an IMP dehydrogenase inhibitor.IMP脱氢酶抑制剂对MCF-7乳腺癌细胞的生长抑制及表型改变诱导作用
Br J Cancer. 1988 Jul;58(1):61-3. doi: 10.1038/bjc.1988.162.
2
Alterations in glycoprotein synthesis and guanosine triphosphate levels associated with the differentiation of HL-60 leukemia cells produced by inhibitors of inosine 5'-phosphate dehydrogenase.与由肌苷5'-磷酸脱氢酶抑制剂产生的HL-60白血病细胞分化相关的糖蛋白合成和鸟苷三磷酸水平的改变。
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Biochemical differences among four inosinate dehydrogenase inhibitors, mycophenolic acid, ribavirin, tiazofurin, and selenazofurin, studied in mouse lymphoma cell culture.在小鼠淋巴瘤细胞培养中对四种肌苷酸脱氢酶抑制剂（霉酚酸、利巴韦林、噻唑呋林和硒唑呋林）的生化差异进行了研究。
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本文引用的文献

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Effects of sodium butyrate and dimethylsulfoxide on biochemical properties of human colon cancer cells.丁酸钠和二甲基亚砜对人结肠癌细胞生化特性的影响。
Cancer. 1980 Mar 15;45(5 Suppl):1185-92. doi: 10.1002/1097-0142(19800315)45:5+<1185::aid-cncr2820451324>3.0.co;2-w.
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Enzymes of purine metabolism in cancer.癌症中嘌呤代谢的酶
Clin Biochem. 1983 Feb;16(1):57-63. doi: 10.1016/s0009-9120(83)94432-6.
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Sodium butyrate produces concordant expression of "early placental" alkaline phosphatase, pregnancy-specific beta 1-glycoprotein and human chronic gonadotropin beta-subunit in a newly established uterine cervical cancer cell line (SKG-IIIa).
肌苷 5'-单磷酸脱氢酶 II 型的过表达介导人骨肉瘤细胞对化疗的耐药性。
PLoS One. 2010 Aug 16;5(8):e12179. doi: 10.1371/journal.pone.0012179.
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Tyrphostins reduce chemotherapy-induced intestinal injury in mice: assessment by a biochemical assay.tyrphostins减轻小鼠化疗诱导的肠道损伤：通过生化分析进行评估
Br J Cancer. 2005 Jan 31;92(2):294-7. doi: 10.1038/sj.bjc.6602324.
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Inhibition of T lymphocyte activation in mice heterozygous for loss of the IMPDH II gene.IMPDH II基因缺失杂合小鼠中T淋巴细胞激活的抑制作用
J Clin Invest. 2000 Aug;106(4):599-606. doi: 10.1172/JCI8669.
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Effects of differentiation-inducing agents on purine nucleotide metabolism in an ovarian cancer cell line.分化诱导剂对卵巢癌细胞系中嘌呤核苷酸代谢的影响。
J Cancer Res Clin Oncol. 1994;120(12):717-22. doi: 10.1007/BF01194269.
7
Novobiocin-induced anti-proliferative and differentiating effects in melanoma B16.新生霉素对黑色素瘤B16的抗增殖和分化作用。
Br J Cancer. 1992 Feb;65(2):183-8. doi: 10.1038/bjc.1992.38.
Int J Cancer. 1983 Sep 15;32(3):267-72. doi: 10.1002/ijc.2910320302.
4
Induction of mammary carcinomas in rats by nitroso-methylurea involves malignant activation of H-ras-1 locus by single point mutations.用亚硝基甲基脲诱导大鼠发生乳腺癌涉及通过单点突变对H-ras-1基因座的恶性激活。
Nature. 1983;306(5944):658-61. doi: 10.1038/306658a0.
5
Intrinsic GTPase activity distinguishes normal and oncogenic ras p21 molecules.内在GTP酶活性区分正常和致癌性Ras p21分子。
Proc Natl Acad Sci U S A. 1984 Sep;81(18):5704-8. doi: 10.1073/pnas.81.18.5704.
6
Purine metabolism in myeloid precursor cells during maturation. Studies with the HL-60 cell line.髓系前体细胞成熟过程中的嘌呤代谢。对HL-60细胞系的研究。
J Clin Invest. 1983 Dec;72(6):1889-900. doi: 10.1172/JCI111152.
7
Differentiation-inducing agents decrease cryptic prolactin receptors in cultured rat mammary tumor cells.分化诱导剂可降低培养的大鼠乳腺肿瘤细胞中隐蔽的催乳素受体水平。
Exp Cell Res. 1984 Nov;155(1):17-23. doi: 10.1016/0014-4827(84)90763-8.
8
The inhibition of nucleic acid synthesis by mycophenolic acid.霉酚酸对核酸合成的抑制作用。
Biochem J. 1969 Jul;113(3):515-24. doi: 10.1042/bj1130515.
9
Experimental antitumor activity and preclinical toxicology of mycophenolic acid.
Cancer Res. 1972 Sep;32(9):1795-802.
10
Direct mutagenesis of Ha-ras-1 oncogenes by N-nitroso-N-methylurea during initiation of mammary carcinogenesis in rats.在大鼠乳腺致癌作用起始阶段，N-亚硝基-N-甲基脲对Ha-ras-1癌基因的直接诱变作用
Nature. 1985;315(6018):382-5. doi: 10.1038/315382a0.