Li Pei-Hsuan, Chen Chun-Chen, Liou Shiow-Wen
Department of Ophthalmology, Taipei City Hospital Renai Branch, Taipei, Taiwan.
Institute of Clinical Medicine, National Yang-Ming University, Taipei, Taiwan.
Taiwan J Ophthalmol. 2016 Jul-Sep;6(3):155-157. doi: 10.1016/j.tjo.2016.04.007. Epub 2016 Jun 1.
A 73-year-old male patient presented with ocular pain, redness, and blurred vision in the left eye, which had been ongoing for more than 2 months. An oval-shaped paracentral corneal ulcer with stromal infiltration and a mild anterior chamber reaction were found. Despite treatment with empiric antibiotics, the lesion progressed and corneal thinning in the middle area was noted. The culture yielded . We therefore prescribed topical 0.2% fluconazole (FCZ) in combination with oral FCZ as an antifungal treatment, following which the stromal infiltration gradually subsided. Complete epithelial-ization was noted on the 8 day after initiating FCZ therapy. There was no recurrent disease in the subsequent 2 years. Our case demonstrates that topical FCZ 0.2% in combination with oral FCZ can successfully treat keratitis and result in a good visual outcome.
一名73岁男性患者出现左眼眼痛、眼红及视力模糊症状，持续2个多月。检查发现角膜旁中央有一椭圆形溃疡，伴有基质浸润及轻度前房反应。尽管使用经验性抗生素治疗，病变仍进展，且发现角膜中部变薄。培养结果显示……因此，我们开具局部0.2%氟康唑（FCZ）联合口服FCZ进行抗真菌治疗，随后基质浸润逐渐消退。开始FCZ治疗后第8天角膜上皮完全愈合。在随后的2年中未出现疾病复发。我们的病例表明，局部0.2%FCZ联合口服FCZ可成功治疗角膜炎并获得良好的视力预后。
