College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou, 310014, China.
Collaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals, Zhejiang University of Technology, Hangzhou, 310014, China.
Appl Microbiol Biotechnol. 2017 Dec;101(23-24):8309-8319. doi: 10.1007/s00253-017-8554-4. Epub 2017 Oct 10.
Rhamnolipids have recently emerged as promising bioactive molecules due to their novel structures, diverse and versatile biological functions, lower toxicity, higher biodegradability, as well as production from renewable resources. The advantages of rhamnolipids make them attractive targets for research in a wide variety of applications. Especially rhamnolipids are likely to possess potential applications of the future in areas such as biomedicine, therapeutics, and agriculture. The purpose of this mini review is to provide a comprehensive prospective of biosurfactant rhamnolipids as potential antimicrobials, immune modulators, and virulence factors, and anticancer agents in the field of biomedicine and agriculture that may meet the ever-increasing future pharmacological treatment and food safety needs in human health.
由于其新颖的结构、多样且多功能的生物学功能、较低的毒性、较高的生物降解性以及可再生资源的生产，鼠李糖脂最近作为有前途的生物活性分子出现。鼠李糖脂的这些优势使其成为各种应用研究的有吸引力的目标。特别是，鼠李糖脂在生物医药、治疗学和农业等领域可能具有未来的潜在应用。本综述的目的是提供生物表面活性剂鼠李糖脂作为潜在的抗菌剂、免疫调节剂和毒力因子，以及在生物医药和农业领域的抗癌剂的全面展望，以满足人类健康中日益增长的未来药理学治疗和食品安全需求。
