Chow Sharon S W, Chan Tommy C Y, Wong Ian Y H, Fan Michelle C Y, Lai Jimmy S M, Ng Alex L K
Department of Ophthalmology, Grantham Hospital, Hong Kong, Hong Kong, SAR.
Department of Ophthalmology and Visual Sciences, Chinese University of Hong Kong, Shatin, Hong Kong, SAR.
Int Ophthalmol. 2018 Dec;38(6):2635-2638. doi: 10.1007/s10792-017-0734-9. Epub 2017 Oct 10.
To report a case series of early postoperative complications following combined accelerated corneal crosslinking (CXL) and trans-epithelial technique in keratoconus.
Eleven eyes underwent accelerated trans-epithelial CXL (18 mW/cm for 5 min). Seven eyes (64%) developed complications in the first week postoperatively. Five eyes had large epithelial defects, and two eyes were complicated with diffuse punctate epithelial erosions. Early transient stromal haze was seen in eyes with epithelial complications. Anterior segment optical coherence tomography showed a faint demarcation line in six eyes (55%) with epithelial complications.
A significant number of eyes developed epithelial complications shortly after combined accelerated trans-epithelial CXL, which defeated the benefits of leaving the epithelium intact.
报告圆锥角膜患者联合加速角膜交联（CXL）和经上皮技术术后早期并发症的病例系列。
11只眼接受了加速经上皮CXL（18 mW/cm，持续5分钟）。7只眼（64%）在术后第一周出现并发症。5只眼有大面积上皮缺损，2只眼并发弥漫性点状上皮糜烂。上皮并发症的眼中可见早期短暂性基质 haze。眼前段光学相干断层扫描显示，6只眼（55%）有上皮并发症，出现一条模糊的分界线。
相当数量的眼睛在联合加速经上皮CXL后不久出现上皮并发症，这抵消了保留完整上皮的益处。
