Kearney H, Cahalane A M, Killeen R P, McGuigan C
Department of Neurology, St. Vincent's University Hospital, Elm Park, Nutley Lane, Dublin 4, D04 T6F4, Ireland.
Department of Radiology, St. Vincent's University Hospital, Elm Park, Nutley Lane, Dublin 4, D04 T6F4, Ireland.
Ir J Med Sci. 2018 May;187(2):493-498. doi: 10.1007/s11845-017-1691-z. Epub 2017 Oct 10.
The diagnosis of multiple sclerosis (MS) is based on a history consistent with demyelination of the central nervous system and corresponding physical signs on examination. However, this diagnosis is supported radiologically using magnetic resonance imaging (MRI). At present, MRI serves as the most reliable and widely available biomarker for the practising clinician to measure disease activity and treatment response in MS. As MRI remains central to both the diagnosis and management of MS, this paper provides proposed guidelines for its use in routine clinical practice.
多发性硬化症（MS）的诊断基于与中枢神经系统脱髓鞘相符的病史及检查时相应的体征。然而，这一诊断需通过磁共振成像（MRI）在影像学上予以支持。目前，MRI是执业临床医生用于测量MS疾病活动度和治疗反应的最可靠且应用最广泛的生物标志物。由于MRI在MS的诊断和管理中均至关重要，本文提供了其在常规临床实践中的使用建议指南。
