Giorgio Antonio, De Stefano Nicola
Department of Medicine, Surgery and Neuroscience, University of Siena, Viale Bracci 2, Siena 53100, Italy.
Department of Medicine, Surgery and Neuroscience, University of Siena, Viale Bracci 2, Siena 53100, Italy.
Neurol Clin. 2018 Feb;36(1):27-34. doi: 10.1016/j.ncl.2017.08.013.
MRI is the most important tool for diagnosis and management of patients with multiple sclerosis (MS). MRI shows high sensitivity for detection of white matter lesions in the central nervous system and specificity for lesion dissemination in space and time. MRI is also used for tracking disease activity, prognostic evaluation, and monitoring the efficacy and safety of disease-modifying treatments. Nonconventional MRI measures (eg, brain atrophy) and quantitative measures of advanced MRI can capture features of MS beyond WM lesions but are not currently implemented in clinical practice. Consensus guidelines on standardized MRI acquisition protocol have been recently published.
磁共振成像（MRI）是诊断和管理多发性硬化症（MS）患者的最重要工具。MRI对检测中枢神经系统白质病变具有高敏感性，对病变在空间和时间上的播散具有特异性。MRI还用于追踪疾病活动、预后评估以及监测疾病修饰治疗的疗效和安全性。非常规MRI测量（如脑萎缩）和先进MRI的定量测量可以捕捉MS中超出白质病变的特征，但目前尚未在临床实践中应用。关于标准化MRI采集协议的共识指南最近已发布。
