Shi Shuo, Gu Lin, Yang Yihu, Yu Haibin, Chen Rui, Xiao Xianglian, Qiu Jun
Ningbo Institute of Materials Technology and Engineering, Chinese Academy of Sciences, Ningbo 315201, Zhejiang, China.
School of Nano Science and Technology, University of Science and Technology of China, Suzhou 215123, Jiangsu, China.
Sheng Wu Gong Cheng Xue Bao. 2016 Jun 25;32(6):831-838. doi: 10.13345/j.cjb.160014.
A series of bio-based thermosetting polyurethanes (Bio-PUs) were synthesized by the crosslinking reaction of polylactide and its copolymers diols with hexamethylene diisocyanate (HDI) trimer. The obtained Bio-PUs were characterized by Fourier Transform Infrared Spectroscopy (FTIR), Differential Scanning Calorimetry (DSC), Thermal Gravimetric Analysis (TGA), universal tensile testing machine and cytotoxicity test. Results indicate that the PLA copolymer (P(LA-co-CL)) diols reduced the glass transition temperature (Tg) of Bio-PUs and improved their thermal stability, compared with PLA diols. The Bio-PUs synthesized from P (LA-co-CL) diols exhibit better mechanical performance and shape memory properties. Especially, Young modulus and elongation at break of the obtained Bio-PUs were 277.7 MPa and 230% respectively; the shape recovery time of the obtained Bio-PUs at body temperature was only 93 s. Furthermore, alamar blue assay results showed that the obtained Bio-PUs had no cell toxicity.
通过聚乳酸及其共聚物二醇与六亚甲基二异氰酸酯（HDI）三聚体的交联反应合成了一系列生物基热固性聚氨酯（Bio-PUs）。采用傅里叶变换红外光谱（FTIR）、差示扫描量热法（DSC）、热重分析（TGA）、万能拉伸试验机和细胞毒性试验对所得Bio-PUs进行了表征。结果表明，与聚乳酸二醇相比，聚乳酸-共-己内酯（P(LA-co-CL)）二醇降低了Bio-PUs的玻璃化转变温度（Tg），并提高了其热稳定性。由P(LA-co-CL)二醇合成的Bio-PUs表现出更好的力学性能和形状记忆性能。特别是，所得Bio-PUs的杨氏模量和断裂伸长率分别为277.7 MPa和230%；所得Bio-PUs在体温下的形状恢复时间仅为93 s。此外，alamar蓝试验结果表明，所得Bio-PUs无细胞毒性。
