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加拿大安大略省 12 年间职业站立和坐姿与突发心脏病之间的关系。

The Relationship Between Occupational Standing and Sitting and Incident Heart Disease Over a 12-Year Period in Ontario, Canada.

机构信息

Institute for Work and Health, Toronto, Ontario, Canada.

Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, Australia.

出版信息

Am J Epidemiol. 2018 Jan 1;187(1):27-33. doi: 10.1093/aje/kwx298.

DOI:10.1093/aje/kwx298
PMID:29020132
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5860480/
Abstract

While a growing body of research is examining the impacts of prolonged occupational sitting on cardiovascular and other health risk factors, relatively little work has examined the effects of occupational standing. The objectives of this paper were to examine the relationship between occupations that require predominantly sitting and those that require predominantly standing and incident heart disease. A prospective cohort study combining responses to a population health survey with administrative health-care records, linked at the individual level, was conducted in Ontario, Canada. The sample included 7,320 employed labor-market participants (50% male) working 15 hours a week or more and free of heart disease at baseline. Incident heart disease was assessed using administrative records over an approximately 12-year follow-up period (2003-2015). Models adjusted for a wide range of potential confounding factors. Occupations involving predominantly standing were associated with an approximately 2-fold risk of heart disease compared with occupations involving predominantly sitting. This association was robust to adjustment for other health, sociodemographic, and work variables. Cardiovascular risk associated with occupations that involve combinations of sitting, standing, and walking differed for men and women, with these occupations associated with lower cardiovascular risk estimates among men but elevated risk estimates among women.

摘要

虽然越来越多的研究正在研究长时间职业性久坐对心血管和其他健康风险因素的影响,但相对较少的工作研究了职业性站立的影响。本文的目的是研究需要主要坐姿和主要站姿的职业与心脏病发病之间的关系。在加拿大安大略省进行了一项前瞻性队列研究,该研究将人群健康调查的反应与行政医疗记录相结合,并在个人层面上进行了关联。样本包括 7320 名每周工作 15 小时或以上、无心脏病的在职劳动力市场参与者(50%为男性)。在大约 12 年的随访期间(2003-2015 年),使用行政记录评估心脏病发病情况。模型调整了广泛的潜在混杂因素。与主要坐姿职业相比,主要站姿职业的心脏病发病风险约为两倍。这种关联在调整其他健康、社会人口统计学和工作变量后仍然稳健。涉及坐姿、站立和行走组合的职业与心血管风险的关联因性别而异,这些职业与男性的心血管风险估计值降低相关,但与女性的心血管风险估计值升高相关。

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