新方法提示短疗程抗生素治疗腹腔内感染具有全球优势。
Novel Method Suggests Global Superiority of Short-Duration Antibiotics for Intra-abdominal Infections.
机构信息
Department of Surgery, Beth Israel Deaconess Medical Center.
Department of Biostatistics, Harvard T. H. Chan School of Public Health, Boston, Massachusetts.
出版信息
Clin Infect Dis. 2017 Oct 16;65(9):1577-1579. doi: 10.1093/cid/cix569.
Abstract
Desirability of outcome ranking and response adjusted for duration of antibiotic risk (DOOR/RADAR) are novel and innovative methods of evaluating data in antibiotic trials. We analyzed data from a noninferiority trial of short-course antimicrobial therapy for intra-abdominal infection (STOP-IT), and results suggest global superiority of short-duration therapy for intra-abdominal infections.
摘要
结局偏好评分和基于抗生素持续时间的应答调整（DOOR/RADAR）是评估抗生素试验数据的新颖创新方法。我们分析了短程抗菌治疗腹腔内感染（STOP-IT）非劣效性试验的数据，结果表明短疗程治疗腹腔内感染具有整体优越性。
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