a Department of Ophthalmology, Faculty of Medicine , Erasmus University , Rotterdam , The Netherlands.
b Prabha Eye Clinic & Research Centre , Vittala International Institute of Ophthalmology , Bangalore , India.
Ocul Immunol Inflamm. 2017 Oct;25(5):710-720. doi: 10.1080/09273948.2017.1353105. Epub 2017 Oct 11.
The viral causes of anterior uveitis (AU) emerged with the use of novel molecular diagnostic tests and serologic tests adapted for small volumes (Goldmann-Witmer Coefficient). The viral causes of AU may be underestimated, and some of the presumed idiopathic AU cases will probably be proven to be of viral origin in the coming years. So far, a viral origin of AU was suspected in patients who presented with unilateral hypertensive AU. It is not clear which clinical presentations should raise a suspicion of viral etiology. There is an overlap in the clinical manifestations of AU caused by viruses and other non-viral forms of AU. A viral cause of AU should be suspected in patients with unilateral AU, exhibiting small or medium sized KPs, some form of iris atrophy, high IOP and early development of a cataract and the definitive diagnosis can be proven by aqueous humor analysis.
新型分子诊断检测和适用于小体积样本的血清学检测（Goldmann-Witmer 系数）的应用，使前葡萄膜炎（AU）的病毒病因浮出水面。 AU 的病毒病因可能被低估了，在未来几年中，一些推测为特发性 AU 的病例可能会被证实为病毒来源。迄今为止，单侧高血压 AU 患者 AU 的病毒来源被怀疑。目前尚不清楚哪种临床表现应怀疑为病毒病因。由病毒和其他非病毒形式 AU 引起的 AU 的临床表现有重叠。单侧 AU 、表现为小或中等 KP、某种形式的虹膜萎缩、高眼压和早期白内障形成的患者应怀疑 AU 的病毒病因，通过房水分析可明确诊断。
