Swiss Research Institute for Public Health and Addiction at Zurich University, Konradstrasse 32, 8031 Zurich, Switzerland.
Institute of Technology Management, University of St. Gallen, Dufourstrasse 40a, 9000 St. Gallen, Switzerland.
J Subst Abuse Treat. 2017 Nov;82:55-66. doi: 10.1016/j.jsat.2017.09.008. Epub 2017 Sep 14.
To test the efficacy of a technology-based integrated smoking cessation and alcohol intervention versus a smoking cessation only intervention in adolescents.
This was a two-arm, parallel-group, cluster-randomised controlled trial with assessments at baseline and six months follow-up. Subjects in both groups received tailored mobile phone text messages to support smoking cessation for 3months, and the option of registering for a program incorporating strategies for smoking cessation centred around a self-defined quit date. Subjects in the integrated intervention group also received tailored feedback regarding their consumption of alcohol and, for binge drinkers, tailored mobile phone text messages encouraging them to maintain their drinking within low-risk limits over a 3-month period. Primary outcome measures were the 7-day point prevalence of smoking abstinence and change in cigarette consumption.
In 360 Swiss vocational and upper secondary school classes, 2127 students who smoked tobacco regularly and owned a mobile phone were invited to participate in the study. Of these, 1471 (69.2%) participated and 6-month follow-up data were obtained for 1116 (75.9%). No significant group differences were observed for any of the primary or secondary outcomes. Moderator analyses revealed beneficial intervention effects concerning 7-day smoking abstinence in participants with higher versus lower alcohol consumption.
Overall, the integrated smoking cessation and alcohol intervention exhibited no advantages over a smoking cessation only intervention, but it might be more effective for the subgroup of adolescent smokers with higher alcohol consumption. Providing a combined smoking cessation and alcohol intervention might be recommended for adolescent smokers with higher-level alcohol consumption.
检验基于技术的综合戒烟和酒精干预与仅戒烟干预在青少年中的疗效。
这是一项两臂、平行组、集群随机对照试验，在基线和 6 个月随访时进行评估。两组受试者均接受个性化的手机短信以支持戒烟 3 个月，并可选择注册一个包含以自定戒烟日期为中心的戒烟策略的项目。综合干预组的受试者还收到了有关其饮酒量的个性化反馈，对于狂饮者，还收到了个性化的手机短信，鼓励他们在 3 个月内将饮酒量保持在低风险范围内。主要结局指标为 7 天点吸烟 abstinence 和吸烟量变化。
在瑞士 360 所职业和高中班级中，邀请了 2127 名经常吸烟且拥有手机的学生参加研究。其中 1471 名（69.2%）参与了研究，并获得了 6 个月的随访数据。在任何主要或次要结局指标上，组间均无显著差异。对参与者的酒精摄入量进行分层分析发现，对于 7 天吸烟 abstinence，干预效果存在有益的组间差异。
总体而言，综合戒烟和酒精干预与仅戒烟干预相比没有优势，但对于酒精摄入量较高的青少年吸烟者亚组可能更有效。对于酒精摄入量较高的青少年吸烟者，提供综合戒烟和酒精干预可能是值得推荐的。
