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Localization of plutonium retention in the small intestine of the neonatal rat, guinea pig, baboon and macaca after Pu-citrate ingestion.

作者信息

Fritsch P, Moutairou K, Lataillade G, Beauvallet M, L'Hullier I, Lepage M, Metivier H, Masse R

机构信息

C.E.A., IPSN, DPS/SPE, Section de Toxicologie et de Cancérologie Expérimentale, Bruyères le Chatel, France.

出版信息

Int J Radiat Biol. 1988 Oct;54(4):537-43. doi: 10.1080/09553008814551981.

DOI:10.1080/09553008814551981
PMID:2902152
Abstract

The retention of Pu-citrate in the gastrointestinal wall was compared at similar post ingestion times after ingestion at 2 days of age by rats and guinea pigs and at 1 to 34 days by neonatal primates. The small intestine was the main site of the Pu retention in all species. In rats and primates, most of the Pu was retained in the distal ileum, whereas in guinea pigs it was more homogeneously distributed. In the rats, Pu was retained in the epithelial cells on villi, but in the guinea pigs and primates it was confined to the macrophages under the epithelial cells in the lacteal region.

摘要

相似文献

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