Sinha Sanjay
Department of Urology, Apollo Hospital, Hyderabad, Telangana, India.
Indian J Urol. 2017 Oct-Dec;33(4):267-275. doi: 10.4103/iju.IJU_358_16.
Neurogenic bladder patients are at long-term risk of secondary upper urinary tract damage. Symptoms are unreliable and follow-up urodynamics is the only method of ascertaining safety of bladder pressures. This review examines the recommendations, shortcomings and utilization of existing guidelines. The evidence with regard to follow-up urodynamics in different settings relevant to neurogenic bladder is evaluated and an algorithm is proposed.
A pubmed search was conducted for studies on follow-up urodynamics in patients with neurogenic bladder. Additional search was made of secondary sources including reviews and guidelines.
The need for follow-up urodynamics should be considered in all patients undergoing an initial assessment and weighed against the risks. Existing guidelines, while unanimous in their recommendation of its utilization, give scant details regarding its incorporation in clinical management. Follow-up urodynamics can document efficacy and identify the need for escalation of therapy in patients on intermittent catheterization and antimuscarinics. Patients with spinal injury, spinal dysraphism and anorectal malformations are at higher risk for upper tract damage. Follow-up urodynamics can help identify patients suitable for intravesical botulinum and mark those destined for failure. Patients undergoing augmentation cystoplasty may be candidates for less aggressive urodynamic follow-up.
Neurogenic bladder is managed by a broad cross-section of physicians. Clear recommendations and a management algorithm are important for improving patient care. Follow-up urodynamics can identify patients at risk, prevent renal dysfunction and improve the quality of life. There is an urgent need for more evidence on this important subject.
神经源性膀胱患者长期面临继发性上尿路损害的风险。症状不可靠,而随访尿动力学是确定膀胱压力安全性的唯一方法。本综述探讨了现有指南的建议、缺点及应用情况。评估了与神经源性膀胱相关的不同情况下随访尿动力学的证据,并提出了一种算法。
在PubMed上搜索关于神经源性膀胱患者随访尿动力学的研究。还对包括综述和指南在内的二手资料进行了额外搜索。
对于所有接受初始评估的患者,都应考虑随访尿动力学的必要性,并权衡其风险。现有指南虽然一致推荐使用随访尿动力学,但在将其纳入临床管理方面提供的细节很少。随访尿动力学可以记录疗效,并确定接受间歇性导尿和抗毒蕈碱药物治疗的患者是否需要升级治疗。脊髓损伤、脊髓发育异常和肛门直肠畸形患者上尿路损害的风险较高。随访尿动力学有助于确定适合膀胱内注射肉毒杆菌的患者,并标记那些注定治疗失败的患者。接受膀胱扩大术的患者可能是随访尿动力学检查不那么积极的对象。
神经源性膀胱由广泛的医生群体管理。明确的建议和管理算法对于改善患者护理很重要。随访尿动力学可以识别有风险的患者,预防肾功能障碍,提高生活质量。迫切需要关于这个重要主题的更多证据。