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印度农村地区6例肱骨远端巨细胞瘤切除术后的肱骨远端假体重建

Endoprosthetic Reconstruction of distal Humerus following Resection of distal Humeral Giant Cell Tumours in Six Patients in Rural India.

作者信息

Balasubramanian N, Gnanasundaram R, Prakasam S

机构信息

Department of Orthopaedics, Saveetha Medical College & University, Chennai, India.

出版信息

Malays Orthop J. 2017 Jul;11(2):25-29. doi: 10.5704/MOJ.1707.001.

DOI:10.5704/MOJ.1707.001
PMID:29021875
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5630047/
Abstract

Giant cell tumour is a commonly occurring benign bone tumour in the Indian population. The common sites of involvement in descending order of frequency are distal femur, proximal tibia, distal radius and proximal humerus. The less commonly occurring sites are distal humerus, pelvis and proximal femur. We present six cases of giant cell tumour involving the distal humerus in rural India. After obtaining a tissue diagnosis by Trucut biopsy and classifying using Enneking's classification, we proceeded to perform wide resection followed by endoprosthetic reconstruction using custom mega prosthesis. We present here six patients (M: F: 2: 4) who were managed by us between 2008-2014. They presented to us with pain around the elbow and restriction in range of movements. They were each noted radiographically to have a lytic lesion involving the distal humerus with the likely diagnosis of giant cell tumour. Closed biopsy was done in all of them to obtain a definitive diagnosis. All patients underwent wide resection and reconstruction using distal humerus custom prosthesis. All patients were followed up at 6, 12, 18 and 24 weeks and thereafter six monthly until the last review. They were assessed using the DASH scoring system. All patients were well with no evidence of recurrence with good to fair functional outcome. We conclude that careful pre-operative planning with meticulous soft tissue dissection and good implant metallurgy and design, these tumours can be treated with good long term functional results.

摘要

骨巨细胞瘤是印度人群中常见的良性骨肿瘤。按发生频率由高到低排列,常见的受累部位依次为股骨远端、胫骨近端、桡骨远端和肱骨近端。较少见的部位是肱骨远端、骨盆和股骨近端。我们报告了印度农村地区6例累及肱骨远端的骨巨细胞瘤病例。通过切割针活检获得组织诊断并采用恩内肯分类法进行分类后,我们进行了广泛切除,随后使用定制的大型假体进行关节置换重建。本文介绍了我们在2008年至2014年间治疗的6例患者(男:女 = 2:4)。他们因肘部周围疼痛和活动范围受限前来就诊。经影像学检查,均发现肱骨远端有溶骨性病变,可能诊断为骨巨细胞瘤。所有患者均进行了闭合活检以明确诊断。所有患者均接受了肱骨远端定制假体的广泛切除和重建手术。所有患者在术后6周、12周、18周和24周进行随访,此后每6个月随访一次,直至最后一次复查。采用DASH评分系统对患者进行评估。所有患者情况良好,无复发迹象,功能结果良好至中等。我们得出结论,通过精心的术前规划、细致的软组织解剖以及良好的植入物冶金和设计,这些肿瘤可以获得良好的长期功能治疗效果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/71fd/5630047/8560d58e518b/moj-11-025-f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/71fd/5630047/e40e885822c9/moj-11-025-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/71fd/5630047/609a7a6b272e/moj-11-025-f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/71fd/5630047/c57e1f942e60/moj-11-025-f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/71fd/5630047/8560d58e518b/moj-11-025-f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/71fd/5630047/e40e885822c9/moj-11-025-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/71fd/5630047/609a7a6b272e/moj-11-025-f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/71fd/5630047/c57e1f942e60/moj-11-025-f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/71fd/5630047/8560d58e518b/moj-11-025-f4.jpg

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本文引用的文献

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Giant cell tumour of the distal humerus: a case report.肱骨远端骨巨细胞瘤:一例报告
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