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伴有周围棕色脂肪的巨大单侧肾上腺肿块：一例报告

Large Unilateral Adrenal Mass with Surrounding Brown Fat: A Case Report.

作者信息

Ologun Gabriel O, Patel Zinal M, Rana Navpreet K, Trecartin Andrew, Shen Alice, Trostle Douglas, Bertsch David

机构信息

General Surgery, Guthrie Clinic/Robert Packer Hospital.

Medicine, Winthrop University Hospital.

出版信息

Cureus. 2017 Aug 9;9(8):e1552. doi: 10.7759/cureus.1552.

DOI:10.7759/cureus.1552
PMID:29021924
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5633263/
Abstract

Pheochromocytomas are rare tumors derived from chromaffin cells located in the adrenal and extra adrenal tissues. Pheochromocytomas are diagnosed biochemically and localized using different imaging modalities. The definitive management is surgical resection. Brown adipose tissues are normally present during fetal development, with regression over time. Brown adipose tissues are thermogenic and usually located in the neck, mediastinum, and retroperitoneum. Here, we report a case of a unilateral pheochromocytoma surrounded by brown fat. The abnormal stimulation of brown fat noted on positive emission tomography scan (PET) resolved after the pheochromocytoma was resected.

摘要

嗜铬细胞瘤是起源于肾上腺和肾上腺外组织中嗜铬细胞的罕见肿瘤。嗜铬细胞瘤通过生化方法诊断，并使用不同的成像方式进行定位。明确的治疗方法是手术切除。棕色脂肪组织通常在胎儿发育期间存在，随着时间推移会退化。棕色脂肪组织具有产热功能，通常位于颈部、纵隔和腹膜后。在此，我们报告一例单侧嗜铬细胞瘤被棕色脂肪包绕的病例。嗜铬细胞瘤切除后，正电子发射断层扫描（PET）上显示的棕色脂肪异常刺激消失。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d64c/5633263/9c1021642f86/cureus-0009-00000001552-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d64c/5633263/3aabab1af733/cureus-0009-00000001552-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d64c/5633263/47ba0316d68e/cureus-0009-00000001552-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d64c/5633263/5316d9bda73b/cureus-0009-00000001552-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d64c/5633263/9c1021642f86/cureus-0009-00000001552-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d64c/5633263/3aabab1af733/cureus-0009-00000001552-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d64c/5633263/47ba0316d68e/cureus-0009-00000001552-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d64c/5633263/5316d9bda73b/cureus-0009-00000001552-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d64c/5633263/9c1021642f86/cureus-0009-00000001552-i04.jpg

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本文引用的文献

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Pheochromocytoma and Paraganglioma: Diagnosis, Genetics, and Treatment.嗜铬细胞瘤和副神经节瘤：诊断、遗传学及治疗
Surg Oncol Clin N Am. 2016 Jan;25(1):119-38. doi: 10.1016/j.soc.2015.08.006.
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Adipocyte lineages: tracing back the origins of fat.脂肪细胞谱系：追溯脂肪的起源
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Update on the management of unusual neuroendocrine tumors: pheochromocytoma and paraganglioma, medullary thyroid cancer and adrenocortical carcinoma.
神经内分泌肿瘤的治疗进展：嗜铬细胞瘤和副神经节瘤、甲状腺髓样癌和肾上腺皮质癌。
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The North American Neuroendocrine Tumor Society consensus guideline for the diagnosis and management of neuroendocrine tumors: pheochromocytoma, paraganglioma, and medullary thyroid cancer.北美神经内分泌肿瘤学会共识指南：神经内分泌肿瘤的诊断和管理-嗜铬细胞瘤、副神经节瘤和甲状腺髓样癌。
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Adrenal pheochromocytoma with surrounding brown fat stimulation.肾上腺嗜铬细胞瘤伴周围棕色脂肪刺激。
AJR Am J Roentgenol. 2009 Jan;192(1):300-1. doi: 10.2214/AJR.08.1166.
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Brown fat imaging with (18)F-6-fluorodopamine PET/CT, (18)F-FDG PET/CT, and (123)I-MIBG SPECT: a study of patients being evaluated for pheochromocytoma.采用（18）F-6-氟多巴胺PET/CT、（18）F-FDG PET/CT及（123）I-MIBG SPECT进行棕色脂肪成像：一项针对嗜铬细胞瘤评估患者的研究。
J Nucl Med. 2007 Jul;48(7):1077-83. doi: 10.2967/jnumed.106.035915. Epub 2007 Jun 15.
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The distribution of brown adipose tissue in the human.人体中棕色脂肪组织的分布。
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Extra-adrenal pheochromocytoma.肾上腺外嗜铬细胞瘤
J Urol. 1992 Jan;147(1):1-10. doi: 10.1016/s0022-5347(17)37119-7.