Nassar Atef M K, Salim Yehia M, Malhat Farag M
Department of Plant Protection, Faculty of Agriculture, Damanhour University, Damanhour, Albeheira 22516, Egypt.
Central Agricultural Pesticide Laboratory, Department of Pesticide Residues and Environmental Pollution, Agricultural Research Center, Dokki, Giza 12618, Egypt.
Pak J Biol Sci. 2016;19(3):95-105. doi: 10.3923/pjbs.2016.95.105.
Pesticides are the first choice by farmers for use against plant pathogens, nevertheless their adverse effects to the environment. Current study was designed to measure pesticides residues in blood of spray farmers and to assess their possible effects. Blood indices and thyroid and reproductive hormones were evaluated in blood of adult male volunteers (20-48 years old). Volunteers were divided to three groups; spray-workers (directly-exposed), farmers who live in the country area (indirectly-exposed) and city inhabitants (not exposed). Spray workers had significantly decreased platelet number (PLT, 33%), ratio of large platelet (P-LCR%, 42%), average platelet volume (MPV, 70%), relative width of the distribution of erythrocytes (PDW, 56%), relative content of monocytes, basophils and eosinophils (MXD, 100%) compared to control group. In addition, blood samples of the exposed group showed significantly decreased PLT (30%), P-LCR (40%), MPV (65%) and PDW (50%) compared to the farmers. Furthermore, levels of testosterone, triiodothyronine and thyroxine hormones of spray workers were significantly low compared with the country residents. Then results were further subjected to canonical discriminant analysis to visualize the interrelationships among variables. Results highlighted the critical need for enforced official interventions that reduce overexposure of spray workers throughout Egypt.
农药是农民用于对抗植物病原体的首选，尽管它们对环境有不利影响。当前的研究旨在测量喷洒农药的农民血液中的农药残留，并评估其可能产生的影响。对成年男性志愿者（20至48岁）的血液指标、甲状腺和生殖激素进行了评估。志愿者被分为三组：喷洒工人（直接接触者）、居住在农村地区的农民（间接接触者）和城市居民（未接触者）。与对照组相比，喷洒工人的血小板数量（PLT，降低了33%）、大血小板比率（P-LCR%，降低了42%）、平均血小板体积（MPV，降低了70%）、红细胞分布宽度（PDW，降低了56%）、单核细胞、嗜碱性粒细胞和嗜酸性粒细胞的相对含量（MXD，增加了100%）显著下降。此外，与农民相比，接触组的血液样本显示PLT（降低了30%）、P-LCR（降低了40%）、MPV（降低了65%）和PDW（降低了50%）显著下降。此外，喷洒工人的睾酮、三碘甲状腺原氨酸和甲状腺素激素水平与农村居民相比显著较低。然后对结果进一步进行典型判别分析，以直观呈现变量之间的相互关系。结果突出表明，迫切需要官方采取强制性干预措施，以减少埃及各地喷洒工人的过度接触。
