Al-Asoufi Ali, Khlaifat Ali, Tarawneh Amjad Al, Alsharafa Khalid, Al-Limoun Muhamad, Khleifat Khaled
Department of Biology, Al-Hussein Bin Talal University, Ma'an, Jordan.
Department of Nursing, Faculty of Prince Aysha for Applied Health and Nursing, Al-Hussein Bin Talal University, Ma'an, Jorda.
Pak J Biol Sci. 2017;20(4):179-188. doi: 10.3923/pjbs.2017.179.188.
The patients with Diabetes Mellitus (DM) have malfunction in bladder which prompt urine accumulation in its pool which serves a decent situation to the microbes to be develop and cause Urinary Tract Infection (UTI). The UTI is the most infectious disease that affects both males and females. This study was designed to detect the bacterial species responsible for UTI in both diabetic and non-diabetic patients in Ma'an province, Jordan.
One hundred sixteen urine samples were investigated to determine UTI-causing bacteria. These samples distributed unequally between diabetic male (12) and diabetic female (25) and also non-diabetic male (13) and non-diabetic female (66).
It was observed that E. coli is responsible for large proportion (44.8%) of UTI in both diabetic (15.5%) and non-diabetic (29.3%) patients. This study showed inequality in the bacterial species that were isolated from both diabetic and non-diabetic samples. However, five bacterial species including E. aerogenes, E. cloacae, C. freundii, A. baumannii and B. subtilis did not exist in all diabetic samples. Treatment of UTI in both diabetic and non-diabetic patients with chloramphenicol (30 μg), ciprofloxacin (5 μg) and vancomycin (30 μg) resulted in more favorability than other antibiotics. At the same time cephalothin (30 μg) was not recommended.
Escherichia coli was the prevailing bacterial infections among those which were isolated from patients with UTI. Certain forms of bacterial infections inclined to be extra common in diabetic patients than others and other infections may be more severe in people with diabetics than in non diabetics.
糖尿病患者膀胱功能失调，导致尿液潴留，为微生物生长创造了良好环境，进而引发尿路感染（UTI）。UTI是一种影响男性和女性的常见传染病。本研究旨在检测约旦马安省糖尿病患者和非糖尿病患者中引起UTI的细菌种类。
对116份尿液样本进行调查，以确定引起UTI的细菌。这些样本在糖尿病男性（12例）、糖尿病女性（25例）、非糖尿病男性（13例）和非糖尿病女性（66例）之间分布不均。
观察发现，大肠杆菌在糖尿病患者（15.5%）和非糖尿病患者（29.3%）的UTI中占很大比例（44.8%）。本研究表明，从糖尿病和非糖尿病样本中分离出的细菌种类存在差异。然而，包括产气肠杆菌、阴沟肠杆菌、弗氏柠檬酸杆菌、鲍曼不动杆菌和枯草芽孢杆菌在内的5种细菌并非在所有糖尿病样本中都存在。用氯霉素（30μg）、环丙沙星（5μg）和万古霉素（30μg）治疗糖尿病和非糖尿病患者的UTI，效果优于其他抗生素。同时，不推荐使用头孢噻吩（30μg）。
大肠杆菌是从UTI患者中分离出的主要细菌感染源。某些形式的细菌感染在糖尿病患者中比在其他患者中更常见，而其他感染在糖尿病患者中可能比在非糖尿病患者中更严重。
