• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

相似文献

1
Network approaches and applications in biology.生物学中的网络方法与应用。
PLoS Comput Biol. 2017 Oct 12;13(10):e1005771. doi: 10.1371/journal.pcbi.1005771. eCollection 2017 Oct.
2
A review on the computational approaches for gene regulatory network construction.基因调控网络构建的计算方法综述。
Comput Biol Med. 2014 May;48:55-65. doi: 10.1016/j.compbiomed.2014.02.011. Epub 2014 Feb 24.
3
Computational biology for cardiovascular biomarker discovery.用于心血管生物标志物发现的计算生物学
Brief Bioinform. 2009 Jul;10(4):367-77. doi: 10.1093/bib/bbp008. Epub 2009 Mar 10.
4
Network systems biology for drug discovery.网络系统生物学在药物发现中的应用。
Clin Pharmacol Ther. 2010 Jul;88(1):120-5. doi: 10.1038/clpt.2010.91. Epub 2010 Jun 2.
5
Practical Approaches to the Development of Biomedical Informatics: the INFOBIOMED Network of Excellence.生物医学信息学发展的实用方法：卓越信息生物医学网络
Stud Health Technol Inform. 2005;116:39-44.
6
Computational approaches for analyzing information flow in biological networks.计算方法在生物网络信息流分析中的应用。
Sci Signal. 2012 Apr 17;5(220):re1. doi: 10.1126/scisignal.2002961.
7
Leading applications and technologies in bioinformatics. Proceedings of the European Molecular Biology Network (EMBnet) Conference 2008: 20th Anniversary Celebration. Martina Franca, Italy. September 18-20, 2008.生物信息学中的前沿应用与技术。《欧洲分子生物学网络（EMBnet）会议2008论文集：20周年庆典》。意大利马蒂纳·弗兰卡。2008年9月18日至20日。
BMC Bioinformatics. 2009;10 Suppl 6:S1-25.
8
A Semantic Web for bioinformatics: goals, tools, systems, applications. Proceedings of the Seventh NETTAB (Network Tools and Applications in Biology) Workshop. June 12-15, 2007. Pisa, Italy.用于生物信息学的语义网：目标、工具、系统与应用。第七届NETTAB（生物学中的网络工具与应用）研讨会会议录。2007年6月12日至15日。意大利比萨。
BMC Bioinformatics. 2008;9 Suppl 4:S1-13.
9
Computational systems biology of aging.衰老的计算系统生物学。
Wiley Interdiscip Rev Syst Biol Med. 2011 Jul-Aug;3(4):414-28. doi: 10.1002/wsbm.126. Epub 2010 Dec 31.
10
Focus issue: series on computational and systems biology.专刊主题：计算与系统生物学系列
Sci Signal. 2011 Sep 6;4(189):eg8. doi: 10.1126/scisignal.2002478.

引用本文的文献

1
A data science practicum to introduce undergraduate students to bioinformatics for research.生物信息学研究导论：数据科学实践
Biochem Mol Biol Educ. 2023 Sep-Oct;51(5):520-528. doi: 10.1002/bmb.21762. Epub 2023 Jul 4.
2
Minimal frustration underlies the usefulness of incomplete regulatory network models in biology.不完全监管网络模型在生物学中的有用性源于最小的挫折。
Proc Natl Acad Sci U S A. 2023 Jan 3;120(1):e2216109120. doi: 10.1073/pnas.2216109120. Epub 2022 Dec 29.
3
Artificial intelligence in cancer target identification and drug discovery.人工智能在癌症靶点识别和药物发现中的应用。
Signal Transduct Target Ther. 2022 May 10;7(1):156. doi: 10.1038/s41392-022-00994-0.
4
Construction of disease-specific cytokine profiles by associating disease genes with immune responses.通过将疾病基因与免疫反应相关联来构建疾病特异性细胞因子谱。
PLoS Comput Biol. 2022 Apr 11;18(4):e1009497. doi: 10.1371/journal.pcbi.1009497. eCollection 2022 Apr.
5
GPCRs Are Optimal Regulators of Complex Biological Systems and Orchestrate the Interface between Health and Disease.G 蛋白偶联受体是复杂生物系统的最佳调节者，协调着健康和疾病之间的界面。
Int J Mol Sci. 2021 Dec 13;22(24):13387. doi: 10.3390/ijms222413387.
6
Challenges and opportunities in network-based solutions for biological questions.网络解决方案在生物问题上的挑战与机遇。
Brief Bioinform. 2022 Jan 17;23(1). doi: 10.1093/bib/bbab437.
7
Co-expression Networks in Predicting Transcriptional Gene Regulation.共表达网络在预测转录基因调控中的应用。
Methods Mol Biol. 2021;2328:1-11. doi: 10.1007/978-1-0716-1534-8_1.
8
Disease-specific interactome alterations via epichaperomics: the case for Alzheimer's disease.通过表观组学改变疾病特异性相互作用组：以阿尔茨海默病为例。
FEBS J. 2022 Apr;289(8):2047-2066. doi: 10.1111/febs.16031. Epub 2021 Jun 12.
9
Finding disease modules for cancer and COVID-19 in gene co-expression networks with the Core&Peel method.利用 Core&Peel 方法在基因共表达网络中寻找癌症和 COVID-19 的疾病模块。
Sci Rep. 2020 Oct 19;10(1):17628. doi: 10.1038/s41598-020-74705-6.
10
Turning genome-wide association study findings into opportunities for drug repositioning.将全基因组关联研究结果转化为药物重新定位的机会。
Comput Struct Biotechnol J. 2020 Jun 12;18:1639-1650. doi: 10.1016/j.csbj.2020.06.015. eCollection 2020.

本文引用的文献

1
BeWith: A Between-Within method to discover relationships between cancer modules via integrated analysis of mutual exclusivity, co-occurrence and functional interactions.BeWith：一种通过对互斥性、共现性和功能相互作用进行综合分析来发现癌症模块之间关系的组内组间方法。
PLoS Comput Biol. 2017 Oct 12;13(10):e1005695. doi: 10.1371/journal.pcbi.1005695. eCollection 2017 Oct.
2
Vicus: Exploiting local structures to improve network-based analysis of biological data.Vicus：利用局部结构改进基于网络的生物数据分析
PLoS Comput Biol. 2017 Oct 12;13(10):e1005621. doi: 10.1371/journal.pcbi.1005621. eCollection 2017 Oct.
3
Incorporating networks in a probabilistic graphical model to find drivers for complex human diseases.将网络纳入概率图形模型以寻找复杂人类疾病的驱动因素。
PLoS Comput Biol. 2017 Oct 12;13(10):e1005580. doi: 10.1371/journal.pcbi.1005580. eCollection 2017 Oct.
4
Network propagation in the cytoscape cyberinfrastructure.细胞图谱网络基础设施中的网络传播
PLoS Comput Biol. 2017 Oct 12;13(10):e1005598. doi: 10.1371/journal.pcbi.1005598. eCollection 2017 Oct.
5
Structural host-microbiota interaction networks.宿主-微生物群结构相互作用网络
PLoS Comput Biol. 2017 Oct 12;13(10):e1005579. doi: 10.1371/journal.pcbi.1005579. eCollection 2017 Oct.
6
Identifying direct contacts between protein complex subunits from their conditional dependence in proteomics datasets.从蛋白质组学数据集中蛋白质复合体亚基的条件依赖性识别它们之间的直接相互作用。
PLoS Comput Biol. 2017 Oct 12;13(10):e1005625. doi: 10.1371/journal.pcbi.1005625. eCollection 2017 Oct.
7
Systematic, network-based characterization of therapeutic target inhibitors.基于网络的治疗靶点抑制剂的系统表征
PLoS Comput Biol. 2017 Oct 12;13(10):e1005599. doi: 10.1371/journal.pcbi.1005599. eCollection 2017 Oct.
8
An Expanded View of Complex Traits: From Polygenic to Omnigenic.复杂性状的扩展观点：从多基因到泛基因
Cell. 2017 Jun 15;169(7):1177-1186. doi: 10.1016/j.cell.2017.05.038.

Network approaches and applications in biology.

作者信息

Ideker Trey, Nussinov Ruth

机构信息

Department of Medicine, University of California San Diego, La Jolla, California, United States of America.

Cancer and Inflammation Program, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, National Cancer Institute at Frederick, Frederick, Maryland, United States of America.

出版信息

PLoS Comput Biol. 2017 Oct 12;13(10):e1005771. doi: 10.1371/journal.pcbi.1005771. eCollection 2017 Oct.

DOI:10.1371/journal.pcbi.1005771
PMID:29023447
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5638228/
Abstract
摘要