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无创性产前检测偶然发现母体多发性骨髓瘤。

An incidental finding of maternal multiple myeloma by non invasive prenatal testing.

机构信息

Medical Genetics and Cytogenetics Department, Carémeau University Hospital Center, Nîmes, France.

Medical Genetics and Cytogenetics Department, University Hospital Center, Montpellier, France.

出版信息

Prenat Diagn. 2017 Dec;37(12):1257-1260. doi: 10.1002/pd.5168. Epub 2017 Nov 28.

Abstract

What is already known about this subject? Non invasive prenatal testing for fetal trisomies 13, 18, and 21 occasionally identifies maternal cancer. What does this study add? A further case of maternal cancer incidentally diagnosed by routine NIPT. Extensive NIPT abnormalities are unlikely to be of fetal origin. Information given to patients should also adequately advise patients on potential incidental findings and might offer the option to opt out of receiving results beyond the trisomy report. International guidelines would improve patient counseling.

摘要

已知关于此主题的信息是什么?胎儿三体 13、18 和 21 的非侵入性产前检测偶尔会发现母体癌症。这项研究增加了什么?另一个通过常规 NIPT 偶然诊断出的母体癌症病例。广泛的 NIPT 异常不太可能来自胎儿。提供给患者的信息还应充分告知患者潜在的偶然发现,并可能提供选择退出接受除三体报告以外的结果的选项。国际指南将改善患者咨询。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6954/5767741/bc86db48d3fb/PD-37-1257-g001.jpg

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