Divisions of Reproductive Endocrinology & Infertility and Minimally Invasive Gynecologic Surgery, Mayo Clinic, Rochester, Minnesota.
Division of Reproductive Endocrinology & Infertility, Cleveland Clinic Foundation, Cleveland, Ohio.
J Minim Invasive Gynecol. 2018 Feb;25(2):218-228. doi: 10.1016/j.jmig.2017.09.020. Epub 2017 Oct 9.
In developed countries Asherman's syndrome is almost always the result of a prior intrauterine operative trauma. This is often asymptomatic but may result in hypo- or amenorrhea and can contribute to infertility and pregnancy complications. We review their etiology, clinical implications, and systems proposed to classify their extent. The numerous methods reported for performing lysis of intrauterine adhesions are summarized along with clinical results. Current strategies to prevent recurrence of intrauterine adhesions have not been conclusively shown to be clinically effective, but the potential for endometrial regeneration using stem cells is an exciting modality under investigation.
在发达国家，Asherman 综合征几乎总是既往宫内手术创伤的结果。这通常是无症状的，但可能导致低或闭经，并可能导致不孕和妊娠并发症。我们回顾了它们的病因、临床意义以及提出的分类系统。总结了报告的用于松解宫腔粘连的多种方法及其临床结果。目前预防宫腔粘连复发的策略尚未被证实具有临床效果，但使用干细胞进行子宫内膜再生是一种令人兴奋的研究模式。
