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《儿童FOUR量表的翻译与验证及其作为结局预测指标的应用:一项初步研究》

[Translation and Validation of the FOUR Scale for Children and its Use as Outcome Predictor: A Pilot Study].

作者信息

Ferreira Sofia Simões, Meireles Daniel, Pinto Alexandra, Abecasis Francisco

机构信息

Serviço de Pediatria Médica. Centro Hospitalar Vila Nova de Gaia/Espinho. Gaia. Portugal.

Serviço de Pediatria Médica. Centro Hospitalar do Porto. Porto. Portugal.

出版信息

Acta Med Port. 2017 Sep 29;30(9):599-607. doi: 10.20344/amp.8052.

Abstract

INTRODUCTION

The Full Outline of UnResponsiveness - FOUR scale has been previously validated to assess impaired consciousness in the adult population. The aim of this study is the translation into Portuguese and validation of the FOUR scale in the pediatric population. The study also compares the FOUR scale and Glasgow coma scale score ratings and the clinical outcome of patients hospitalized in Pediatric Intensive Care Units.

MATERIAL AND METHODS

This study prospectively rated patients admitted to the Pediatric Intensive Care Units with impaired consciousness during one year. Both scales were applied daily to patients by three types of examiners: intensivists, residents and nurses, from the moment of admission until clinical discharge. Neurological sequelae was evaluated using the King's Outcome Scale for Childhood Head Injury - KOSCHI.

RESULTS

Twenty seven patients between one and 17 years of age were included. Both scales are reliable and inter-rater reliability was greater for the FOUR score. Glasgow coma scale showed a minimum score in eight evaluations, whereas the FOUR scale obtained the minimum score in only two of these evaluations. In both scales there was a strong association between the admission score and the patient's outcome (area under curve FOUR = 0.939, versus Glasgow coma scale = 0.925).

DISCUSSION

The FOUR scale provides more neurological information than Glasgow coma scale in patients with impaired consciousness and has prognostic interest.

CONCLUSION

The FOUR scale can be applied in patients admitted with impaired consciousness in Pediatric Intensive Care Units. We think that a multicenter study would be very beneficial for confirming and generalizing these results.

摘要

引言

无反应性全面评估量表(FOUR量表)此前已被验证可用于评估成年人群的意识障碍。本研究旨在将FOUR量表翻译成葡萄牙语并在儿科人群中进行验证。该研究还比较了FOUR量表和格拉斯哥昏迷量表的评分以及儿科重症监护病房住院患者的临床结局。

材料与方法

本研究前瞻性地对在一年期间入住儿科重症监护病房且有意识障碍的患者进行评分。从入院到临床出院,由三种类型的检查人员(重症监护医生、住院医生和护士)每天对患者应用这两种量表。使用儿童头部损伤国王结局量表(KOSCHI)评估神经后遗症。

结果

纳入了27例年龄在1至17岁之间的患者。两种量表都具有可靠性,且FOUR量表的评分者间信度更高。格拉斯哥昏迷量表在8次评估中显示出最低分,而FOUR量表仅在其中2次评估中获得最低分。在两种量表中,入院评分与患者结局之间均存在强关联(FOUR量表曲线下面积 = 0.939,格拉斯哥昏迷量表曲线下面积 = 0.925)。

讨论

在意识障碍患者中,FOUR量表比格拉斯哥昏迷量表提供了更多的神经学信息,且具有预后参考价值。

结论

FOUR量表可应用于入住儿科重症监护病房且有意识障碍的患者。我们认为多中心研究对于证实和推广这些结果将非常有益。

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