von Kobyletzki Laura Beate, Beckman Linda, Smeeth Liam, McKee Martin, Quint Jennifer K, Abuabara Katrina, Langan Sinead
Department of Dermatology, Lund University, Skåne University Hospital, Malmö, Sweden.
Department of Public Health Sciences, Karlstads Universitet, Karlstad, Sweden.
BMJ Open. 2017 Oct 11;7(10):e017245. doi: 10.1136/bmjopen-2017-017245.
Childhood allergic diseases may prevent affected children from achieving their academic potential. Potential mechanisms include absence from school due to illness and medical appointments. Experience of symptoms in classes or leisure time, and stigma associated with visible signs and symptoms, including skin disease, requirements for medication during school time or the need for specific diets, may also contribute to reduced educational attainment. Studies have investigated the association between specific allergic diseases and educational attainment. The aim of this study is to systematically review the literature on allergic diseases, educational attainment and occupational status, and if possible, calculate meta-analytic summary estimates for the associations.
Systematic electronic searches in Medline, EMBASE, Cochrane, Cumulative Index to Nursing & Allied Health Literature (CINAHL), PsycINFO and education Resources Information Center (ERIC); hand search in reference lists of included papers and conference reports; search for unpublished studies in clinical trial registers and the New York Academy of Medicine Grey Literature Report; data extraction; and study quality assessment (Newcastle-Ottawa Scale) will be performed.
Data will be summarised descriptively, and meta-analysis including meta-regression to explore sources of heterogeneities will be performed if possible.
Dissemination in a peer-reviewed, open-access, international scientific journal is planned.
CRD42017058036.
儿童过敏性疾病可能会妨碍患病儿童发挥其学术潜力。潜在机制包括因病缺课和就医。在课堂或休闲时间出现症状，以及与可见体征和症状相关的污名，包括皮肤病、上学期间用药需求或特殊饮食需求，也可能导致学业成绩下降。已有研究调查了特定过敏性疾病与学业成绩之间的关联。本研究的目的是系统回顾关于过敏性疾病、学业成绩和职业状况的文献，并在可能的情况下计算这些关联的荟萃分析汇总估计值。
将在Medline、EMBASE、Cochrane、护理及相关健康文献累积索引（CINAHL）、PsycINFO和教育资源信息中心（ERIC）进行系统的电子检索；对纳入论文的参考文献列表和会议报告进行手工检索；在临床试验注册库和纽约医学院灰色文献报告中搜索未发表的研究；进行数据提取；并进行研究质量评估（纽卡斯尔-渥太华量表）。
将对数据进行描述性总结，并在可能的情况下进行荟萃分析，包括荟萃回归以探索异质性来源。
计划在同行评审的开放获取国际科学期刊上发表。
PROSPERO注册号：CRD42017058036。
