Shapiro Gilla K, Perez Samara, Naz Anila, Tatar Ovidiu, Guichon Juliet R, Amsel Rhonda, Zimet Gregory D, Rosberger Zeev
Department of Psychology, McGill University, Montreal, Quebec, Canada.
Lady Davis Institute for Medical Research, Jewish General Hospital, Montreal, Quebec, Canada.
BMJ Open. 2017 Oct 11;7(10):e017814. doi: 10.1136/bmjopen-2017-017814.
Human papillomavirus (HPV), a sexually transmitted infection, can cause anogenital warts and a number of cancers. To prevent morbidity and mortality, three vaccines have been licensed and are recommended by Canada's National Advisory Committee on Immunisation (for girls since 2007 and boys since 2012). Nevertheless, HPV vaccine coverage in Canada remains suboptimal in many regions. This study will be the first to concurrently examine the correlates of HPV vaccine decision-making in parents of school-aged girls and boys and evaluate changes in parental knowledge, attitudes and behaviours over time.
Using a national, online survey utilising theoretically driven constructs and validated measures, this study will identify HPV vaccine coverage rates and correlates of vaccine decision-making in Canada at two time points (August-September 2016 and June-July 2017). 4606 participants will be recruited to participate in an online survey through a market research and polling firm using email invitations. Data cleaning methods will identify inattentive or unmotivated participants.
The study received research ethics board approval from the Research Review Office, Integrated Health and Social Services University Network for West-Central Montreal (CODIM-FLP-16-219). The study will adopt a multimodal approach to disseminate the study's findings to researchers, clinicians, cancer and immunisation organisations and the public in Canada and internationally.
人乳头瘤病毒（HPV）是一种性传播感染，可引发肛门生殖器疣和多种癌症。为预防发病和死亡，三种疫苗已获许可，加拿大国家免疫咨询委员会也予以推荐（自2007年起针对女孩，自2012年起针对男孩）。然而，加拿大许多地区的HPV疫苗接种覆盖率仍未达到最佳水平。本研究将首次同时考察学龄女童和男童父母做出HPV疫苗接种决策的相关因素，并评估父母的知识、态度和行为随时间的变化情况。
本研究将通过一项全国性在线调查，运用理论驱动的结构和经过验证的测量方法，在两个时间点（2016年8月至9月和2017年6月至7月）确定加拿大的HPV疫苗接种覆盖率以及疫苗接种决策的相关因素。将通过一家市场研究和民意调查公司，利用电子邮件邀请4606名参与者参与在线调查。数据清理方法将识别注意力不集中或积极性不高的参与者。
该研究已获得蒙特利尔中西部综合健康与社会服务大学网络研究审查办公室研究伦理委员会的批准（CODIM-FLP-16-219）。该研究将采用多模式方法，向加拿大和国际上的研究人员、临床医生、癌症和免疫组织以及公众传播研究结果。
