a Lady Davis Institute for Medical Research, Jewish General Hospital , Montreal , Quebec , Canada.
b Department of Psychology, McGill University , Montreal , Quebec , Canada.
Hum Vaccin Immunother. 2019;15(7-8):1803-1814. doi: 10.1080/21645515.2019.1575711. Epub 2019 Apr 22.
: Achieving optimal human papillomavirus (HPV) vaccine uptake can be delayed by parents' HPV vaccine hesitancy, which is as a multi-stage intention process rather than a dichotomous (vaccinated/not vaccinated) outcome. Our objective was to longitudinally explore HPV related attitudes, beliefs and knowledge and to estimate the effect of psychosocial factors on HPV vaccine acceptability in HPV vaccine hesitant parents of boys and girls. : We used an online survey to collect data from a nationally representative sample of Canadian parents of 9-16 years old boys and girls in September 2016 and July 2017. Informed by the Precaution Adoption Process Model, we categorized HPV vaccine hesitant parents into and . Measures included sociodemographics, health behaviors and validated scales for HPV and HPV vaccine related attitudes, beliefs and knowledge. Predictors of HPV vaccine acceptability were assessed with binomial logistic regression. : Parents of boys and girls categorized as "flexible" hesitant (i.e., ) changed over time their HPV related attitudes, behaviors, knowledge and intentions to vaccinate compared to "rigid" hesitant (i.e., ) who remained largely unchanged. In "flexible" hesitant, greater social influence to vaccinate (e.g., from family), increased HPV knowledge, higher family income, white ethnicity and lower perception of harms (e.g., vaccine safety), were associated with higher HPV vaccine acceptability. : HPV vaccine hesitant parents are not a homogenous group. We have identified significant predictors of HPV vaccine acceptability in "flexible" hesitant parents. Further research is needed to estimate associations between psychosocial factors and vaccine acceptability in "rigid" hesitant parents.
: 父母对接种 HPV 疫苗的犹豫不决会延迟 HPV 疫苗的最佳接种率，因为这种犹豫是一个多阶段的意图过程，而不是二选一（接种/未接种）的结果。我们的目的是纵向探讨 HPV 相关态度、信念和知识，并估计心理社会因素对 HPV 疫苗犹豫的男孩和女孩的父母对 HPV 疫苗可接受性的影响。: 我们使用在线调查于 2016 年 9 月和 2017 年 7 月从加拿大全国代表性的 9-16 岁男孩和女孩的父母中收集数据。根据预防接种过程模型，我们将 HPV 疫苗犹豫的父母分为“灵活”犹豫者（即）和“固执”犹豫者（即）。测量包括社会人口统计学、健康行为和 HPV 及 HPV 疫苗相关态度、信念和知识的验证量表。使用二项逻辑回归评估 HPV 疫苗可接受性的预测因素。: 与“固执”犹豫者（即）相比，男孩和女孩的父母被归类为“灵活”犹豫者（即），他们的 HPV 相关态度、行为、知识和接种意愿随时间发生变化。在“灵活”犹豫者中，更多的接种社会影响（例如，来自家庭）、更高的 HPV 知识、更高的家庭收入、白种人种族和更低的危害感知（例如，疫苗安全性）与更高的 HPV 疫苗可接受性相关。: HPV 疫苗犹豫的父母不是一个同质群体。我们已经确定了“灵活”犹豫者中 HPV 疫苗可接受性的重要预测因素。需要进一步研究来估计“固执”犹豫者中心理社会因素与疫苗可接受性之间的关联。
