Universidade Católica Portuguesa, CBQF - Centro de Biotecnologia e Química Fina - Laboratório Associado, Escola Superior de Biotecnologia, Rua Arquiteto Lobão Vital, Apartado 2511, Porto 4202-401, Portugal.
Research Center for Natural Resources and Sustainability (CIRENYS), Bernardo O'Higgins University, Fábrica N° 1990, Segundo Piso, Santiago de Chile, Chile.
Biosci Rep. 2017 Nov 15;37(6). doi: 10.1042/BSR20170705. Print 2017 Nov 22.
During many years, the milk fat has been unfairly undervalued due to its association with higher levels of cardiovascular diseases, dyslipidaemia or obesity, among others. However, currently, this relationship is being re-evaluated because some of the dairy lipid components have been attributed potential health benefits. Due to this, and based on the increasing incidence of cancer in our society, this review work aims to discuss the state of the art concerning scientific evidence of milk lipid components and reported anticancer properties. Results from the and experiments suggest that specific fatty acids (FA) (as butyric acid and conjugated linoleic acid (CLA), among others), phospholipids and sphingolipids from milk globule membrane are potential anticarcinogenic agents. However, their mechanism of action remains still unclear due to limited and inconsistent findings in human studies.
多年来,由于牛奶脂肪与心血管疾病、血脂异常或肥胖等更高水平有关,其一直被不公平地低估。然而,目前这种关系正在重新评估,因为一些乳制品脂质成分被认为具有潜在的健康益处。由于这一点,并且基于我们社会中癌症发病率的增加,这项综述工作旨在讨论有关牛奶脂质成分和报道的抗癌特性的科学证据的最新情况。和实验的结果表明,特定脂肪酸(FA)(如丁酸和共轭亚油酸(CLA)等)、乳球蛋白膜中的磷脂和鞘脂是潜在的抗癌剂。然而,由于在人体研究中发现的结果有限且不一致,它们的作用机制仍不清楚。