Sayad Fathi Sara, Zaminy Arash
Department of Anatomical Sciences, School of Medicine, Guilan University of Medical Sciences, Rasht 41996-13769, Iran.
World J Stem Cells. 2017 Sep 26;9(9):144-151. doi: 10.4252/wjsc.v9.i9.144.
Peripheral nerve injury has remained a substantial clinical complication with no satisfactory treatment options. Despite the great development in the field of microsurgery, some severe types of neural injuries cannot be treated without causing tension to the injured nerve. Thus, current studies have focused on the new approaches for the treatment of peripheral nerve injuries. Stem cells with the ability to differentiate into a variety of cell types have brought a new perspective to this matter. In this review, we will discuss the use of three main sources of mesenchymal stem cells in the treatment of peripheral nerve injuries.
周围神经损伤一直是一个严重的临床并发症,目前尚无令人满意的治疗方法。尽管显微外科领域取得了巨大进展,但某些严重类型的神经损伤在治疗时难免会对受损神经造成张力。因此,目前的研究集中在治疗周围神经损伤的新方法上。具有分化为多种细胞类型能力的干细胞为这一问题带来了新的视角。在这篇综述中,我们将讨论间充质干细胞的三种主要来源在治疗周围神经损伤中的应用。