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膀胱癌膀胱内灌注卡介苗后发生的全身性卡介苗病。

Systemic BCG-osis following intravesical BCG instillation for bladder carcinoma.

作者信息

Liaw Frank, Tan Yan Yu, Hendry David

机构信息

Department of Urology Queen Elizabeth University Hospital Glasgow G51 4TF UK.

Department of Gastroenterology Monklands Hospital Airdrie ML6 0JS UK.

出版信息

Clin Case Rep. 2017 Aug 15;5(10):1569-1572. doi: 10.1002/ccr3.1129. eCollection 2017 Oct.

DOI:10.1002/ccr3.1129
PMID:29026546
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5628231/
Abstract

Intravesical instillation of Bacillus Calmette-Guérin (BCG) has been shown to be an effective form of immunotherapy for bladder cancer. This case report describes a patient who develops systemic BCG-osis following intravesical BCG instillation and demonstrates the importance of being aware of more severe complications associated with BCG immunotherapy.

摘要

膀胱内灌注卡介苗(BCG)已被证明是一种有效的膀胱癌免疫治疗方式。本病例报告描述了一名患者在膀胱内灌注BCG后发生全身性BCG病,并证明了认识到与BCG免疫治疗相关的更严重并发症的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4986/5628231/dbda60ad54b5/CCR3-5-1569-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4986/5628231/5c1807dcdabc/CCR3-5-1569-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4986/5628231/dbda60ad54b5/CCR3-5-1569-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4986/5628231/5c1807dcdabc/CCR3-5-1569-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4986/5628231/dbda60ad54b5/CCR3-5-1569-g002.jpg

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本文引用的文献

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Urol Int. 2016;96(1):20-4. doi: 10.1159/000430501. Epub 2015 Jul 17.
2
Bacillus Calmette-Guérin (BCG) infection following intravesical BCG administration as adjunctive therapy for bladder cancer: incidence, risk factors, and outcome in a single-institution series and review of the literature.卡介苗(BCG)膀胱内灌注作为膀胱癌辅助治疗后的感染:单中心系列研究中的发病率、危险因素及结局,并对文献进行综述
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Mycobacterium bovis bacille Calmette-Guerin-derived extracellular vesicles as an alternative to live BCG immunotherapy.
牛分枝杆菌卡介苗衍生的细胞外囊泡作为活卡介苗免疫治疗的替代物。
Clin Exp Med. 2023 Jun;23(2):519-527. doi: 10.1007/s10238-022-00794-4. Epub 2022 Jan 25.
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Testicular tuberculosis: An uncommon complication after treatment of urothelial carcinoma.睾丸结核:尿路上皮癌治疗后的一种罕见并发症。
Radiol Case Rep. 2020 Sep 11;15(11):2285-2293. doi: 10.1016/j.radcr.2020.07.030. eCollection 2020 Nov.
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Disseminated BCG sepsis following intravesical therapy for Bladder Carcinoma: A case report and review of literature.膀胱癌膀胱内灌注治疗后播散性卡介苗败血症:一例报告并文献复习
J Community Hosp Intern Med Perspect. 2020 May 21;10(2):168-170. doi: 10.1080/20009666.2020.1742475.
6
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Eur J Med Chem. 2020 Jan 1;185:111832. doi: 10.1016/j.ejmech.2019.111832. Epub 2019 Oct 31.
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Indian J Urol. 2011 Apr;27(2):252-61. doi: 10.4103/0970-1591.82846.
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Can J Urol. 2011 Jun;18(3):5671-5.
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Novel insights into the mechanism of action of intravesical immunomodulators.对膀胱内免疫调节剂作用机制的新见解。
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J Urol. 2002 Nov;168(5):1964-70. doi: 10.1016/S0022-5347(05)64273-5.