Powell Priscilla, Vitug Gaile, Castro-Silva Fernando, Ray Anish
Weatherford Regional Medical Center Weatherford Texas.
University of Texas Health Science Center at San Antonio San Antonio Texas.
Clin Case Rep. 2017 Sep 1;5(10):1664-1667. doi: 10.1002/ccr3.1136. eCollection 2017 Oct.
Langerhans cell histiocytosis is a dendritic cell disorder with a wide spectrum of severity and presentations. Histopathology typically demonstrates a proliferation of Langerhans cells and a lymphohistiocytic inflammatory infiltrate with eosinophils. The diagnosis is supported by immunohistochemistry with the cell markers S100, CD1a, CD68, and Langerin [, 126, 2015, 26 and , 331, 1994, 154].
朗格汉斯细胞组织细胞增多症是一种具有广泛严重程度和临床表现的树突状细胞疾病。组织病理学通常显示朗格汉斯细胞增殖以及伴有嗜酸性粒细胞的淋巴细胞组织细胞性炎性浸润。免疫组织化学检测细胞标志物S100、CD1a、CD68和朗格素支持该诊断[, 126, 2015, 26和, 331, 1994, 154]。