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使用 APCEDEN（基于树突状细胞的疫苗）使口咽罕见腺癌完全缓解：一例病例报告。

Complete remission of rare adenocarcinoma of the oropharynx with APCEDEN (dendritic cell-based vaccine): a case report.

作者信息

Kumar Chaitanya, Kohli Sakshi, Chiliveru Srikanth, Jain Minish, Sharan Bandana

机构信息

R&D APAC Biotech Pvt Ltd Gurgaon India.

Medical Oncology Ruby Hall Clinic Pune India.

出版信息

Clin Case Rep. 2017 Sep 7;5(10):1692-1696. doi: 10.1002/ccr3.1169. eCollection 2017 Oct.

DOI:10.1002/ccr3.1169
PMID:29026574
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5628247/
Abstract

APCEDEN is an autologous monocyte-derived dendritic cell-based immunotherapy. A 58-year-old man with adenocarcinoma of oropharynx shows complete remission after receiving APCEDEN in conjunction with Geftinib validated by reduction in size, whereas Gefitinib alone lead to disease progression.

摘要

APCEDEN是一种基于自体单核细胞衍生树突状细胞的免疫疗法。一名58岁的口咽腺癌男性患者在接受APCEDEN联合吉非替尼治疗后，肿瘤大小缩小，显示出完全缓解，而单独使用吉非替尼则导致疾病进展。

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2
The Neutrophil/Lymphocyte Ratio at Diagnosis Is Significantly Associated with Survival in Metastatic Pancreatic Cancer Patients.诊断时的中性粒细胞/淋巴细胞比值与转移性胰腺癌患者的生存率显著相关。
Int J Mol Sci. 2017 Mar 29;18(4):730. doi: 10.3390/ijms18040730.
3
The neutrophil-to-lymphocyte ratio: a narrative review.中性粒细胞与淋巴细胞比值：一篇叙述性综述。
Ecancermedicalscience. 2016 Dec 12;10:702. doi: 10.3332/ecancer.2016.702. eCollection 2016.
4
Immune-related Adverse Events of Dendritic Cell Vaccination Correlate With Immunologic and Clinical Outcome in Stage III and IV Melanoma Patients.树突状细胞疫苗接种的免疫相关不良事件与 III 期和 IV 期黑色素瘤患者的免疫及临床结局相关。
J Immunother. 2016 Jul-Aug;39(6):241-8. doi: 10.1097/CJI.0000000000000127.
5
Dendritic Cell-Secreted Cytotoxic T-Lymphocyte-Associated Protein-4 Regulates the T-cell Response by Downmodulating Bystander Surface B7.树突状细胞分泌的细胞毒性T淋巴细胞相关蛋白4通过下调旁观者表面B7来调节T细胞反应。
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6
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