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粒细胞集落刺激因子在治疗甲巯咪唑所致粒细胞缺乏症中的应用：一例报告

Use of granulocyte colony-stimulating factor in the treatment of methimazole-induced agranulocytosis: a case report.

作者信息

Birmingham Asha, Mancuso Carissa, Williams Craig

机构信息

Department of Pharmacy Oregon Health & Science University 3181 S.W. Sam Jackson Park Rd., Mail Code: CR 9-4 Portland Oregon 97239 USA.

Department of Pharmacy Memorial Sloan Kettering Cancer Center 1114 1st Ave, 2nd floor New York City New York 10065 USA.

出版信息

Clin Case Rep. 2017 Sep 8;5(10):1701-1705. doi: 10.1002/ccr3.1124. eCollection 2017 Oct.

DOI:10.1002/ccr3.1124
PMID:29026576
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5628249/
Abstract

A comparison of this case to previously published reports suggests that granulocyte colony-stimulating factor may be associated with improved prognosis in severe antithyroid drug-induced neutropenia, and that weight-based doses could be an appropriate strategy.

摘要

将该病例与先前发表的报告进行比较表明，粒细胞集落刺激因子可能与严重抗甲状腺药物所致中性粒细胞减少症的预后改善相关，且基于体重的剂量可能是一种合适的策略。

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1
Use of granulocyte colony-stimulating factor in the treatment of methimazole-induced agranulocytosis: a case report.粒细胞集落刺激因子在治疗甲巯咪唑所致粒细胞缺乏症中的应用：一例报告
Clin Case Rep. 2017 Sep 8;5(10):1701-1705. doi: 10.1002/ccr3.1124. eCollection 2017 Oct.
2
Granulocyte colony-stimulating factor treatment of antithyroid drug-induced granulocytopenia.粒细胞集落刺激因子治疗抗甲状腺药物所致粒细胞减少症
Arch Intern Med. 1993 Feb 22;153(4):509-14.
3
Treatment of antithyroid drug-induced agranulocytosis by granulocyte colony-stimulating factor: a case of primum non nocere.粒细胞集落刺激因子治疗抗甲状腺药物所致粒细胞缺乏症：一例遵循不伤害原则的病例
Thyroid. 1999 Oct;9(10):1033-5. doi: 10.1089/thy.1999.9.1033.
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Agranulocytosis induced by antithyroid therapy: effects of treatment with granulocyte colony stimulating factor.抗甲状腺治疗所致粒细胞缺乏症：粒细胞集落刺激因子治疗的效果
Clin Investig. 1994 May;72(5):390-2. doi: 10.1007/BF00252834.
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Methimazole-induced agranulocytosis treated with recombinant human granulocyte colony-stimulating factor (rhG-CSF): a case report.重组人粒细胞集落刺激因子（rhG-CSF）治疗甲巯咪唑所致粒细胞缺乏症：1例报告
Zhonghua Yi Xue Za Zhi (Taipei). 1995 Nov;56(5):351-5.
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[Agranulocytosis induced by synthetic antithyroid drugs: efficacy of hematopoietic growth factors].[合成抗甲状腺药物所致粒细胞缺乏症：造血生长因子的疗效]
Ann Endocrinol (Paris). 1994;55(1):39-42.
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Adverse Drug React Toxicol Rev. 1996 Jun;15(2):119-24.
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Methimazole-induced agranulocytosis treated with recombinant human granulocyte colony-stimulating factor (G-CSF).用重组人粒细胞集落刺激因子（G-CSF）治疗甲巯咪唑引起的粒细胞缺乏症。
Thyroid. 1994 Fall;4(3):295-6. doi: 10.1089/thy.1994.4.295.
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[Retrospective analysis of 18 cases with agranulocytosis induced by antithyroid drugs].[抗甲状腺药物致粒细胞缺乏症18例回顾性分析]
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Treatment of methimazole-induced agranulocytosis using recombinant human granulocyte colony-stimulating factor (rhG-CSF).使用重组人粒细胞集落刺激因子（rhG-CSF）治疗甲巯咪唑引起的粒细胞缺乏症。
J Clin Endocrinol Metab. 1993 Nov;77(5):1356-60. doi: 10.1210/jcem.77.5.7521347.

引用本文的文献

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Concomitant methimazole-induced agranulocytosis and cholestatic jaundice in a young woman.一位年轻女性同时发生甲巯咪唑诱导的粒细胞缺乏症和胆汁淤积性黄疸。
BMJ Case Rep. 2022 Aug 25;15(8):e250113. doi: 10.1136/bcr-2022-250113.

本文引用的文献

1
Characteristics of Korean Patients with Antithyroid Drug-Induced Agranulocytosis: A Multicenter Study in Korea.韩国抗甲状腺药物诱导粒细胞缺乏症患者的特征：韩国多中心研究。
Endocrinol Metab (Seoul). 2015 Dec;30(4):475-80. doi: 10.3803/EnM.2015.30.4.475. Epub 2015 Sep 22.
2
Nonchemotherapy drug-induced neutropenia and agranulocytosis: could medications be the culprit?非化疗药物所致中性粒细胞减少症和粒细胞缺乏症：药物会是罪魁祸首吗？
J Pharm Pract. 2014 Oct;27(5):447-52. doi: 10.1177/0897190014546115. Epub 2014 Aug 14.
3
Subcutaneous versus intravenous granulocyte colony stimulating factor for the treatment of neutropenia in hospitalized hemato-oncological patients: randomized controlled trial.皮下注射与静脉注射粒细胞集落刺激因子治疗住院血液肿瘤患者中性粒细胞减少症：随机对照试验。
Am J Hematol. 2014 Mar;89(3):243-8. doi: 10.1002/ajh.23622.
4
The relationship between bone marrow characteristics and the clinical prognosis of antithyroid drug-induced agranulocytosis.抗甲状腺药物诱导粒细胞缺乏症的骨髓特征与临床预后的关系。
Endocr J. 2013;60(2):185-9. doi: 10.1507/endocrj.ej12-0332. Epub 2012 Oct 27.
5
Hyperthyroidism and other causes of thyrotoxicosis: management guidelines of the American Thyroid Association and American Association of Clinical Endocrinologists.甲状腺功能亢进症及其他原因所致甲状腺毒症：美国甲状腺协会和美国临床内分泌医师学会管理指南。
Thyroid. 2011 Jun;21(6):593-646. doi: 10.1089/thy.2010.0417. Epub 2011 Apr 21.
6
Clinical presentation and management of drug-induced agranulocytosis.药物诱导性粒细胞缺乏症的临床表现与治疗。
Expert Rev Hematol. 2011 Apr;4(2):143-51. doi: 10.1586/ehm.11.12.
7
Antithyroid drug-induced agranulocytosis.抗甲状腺药物所致粒细胞缺乏症。
J Chin Med Assoc. 2009 Aug;72(8):438-41. doi: 10.1016/S1726-4901(09)70402-2.
8
Systematic review: agranulocytosis induced by nonchemotherapy drugs.系统评价：非化疗药物所致粒细胞缺乏症
Ann Intern Med. 2007 May 1;146(9):657-65. doi: 10.7326/0003-4819-146-9-200705010-00009.
9
Antithyroid drug-induced agranulocytosis: how has granulocyte colony-stimulating factor changed therapy?抗甲状腺药物所致粒细胞缺乏症：粒细胞集落刺激因子如何改变治疗方法？
Thyroid. 2005 Mar;15(3):292-7. doi: 10.1089/thy.2005.15.292.
10
Antithyroid drugs.抗甲状腺药物
N Engl J Med. 2005 Mar 3;352(9):905-17. doi: 10.1056/NEJMra042972.