使用稳定剂量奥氮平的患者发生神经阻滞剂恶性综合征。
Neuroleptic malignant syndrome in a patient with stable dose of olanzapine.
作者信息
Sahoo Manoj Kumar, Kamath Sangita, Sharan Abhijeet
机构信息
Department of Psychiatry, Tata Main Hospital, Jamshedpur, Jharkhand, India.
Department of Medicine, Tata Main Hospital, Jamshedpur, Jharkhand, India.
出版信息
J Family Med Prim Care. 2017 Jan-Mar;6(1):158-160. doi: 10.4103/2249-4863.214969.
Abstract
Neuroleptic malignant syndrome (NMS), a potentially fatal consequence due to typical neuroleptics, has been described so far. In the past few years, there has been increased use of atypical antipsychotic drugs. Cases of NMS related to atypical neuroleptics, such as olanzapine, are less common in spite of increasing cases reported in literatures. Here, we report a case of NMS in a patient with bipolar affective disorder on maintenance treatment with 5 mg olanzapine for the last 7 year. He was successfully treated with bromocriptine and discharged in stable condition in 10 days.
摘要
迄今为止，已报道了由典型抗精神病药物引起的一种潜在致命后果——神经阻滞剂恶性综合征（NMS）。在过去几年中，非典型抗精神病药物的使用有所增加。尽管文献中报道的与非典型抗精神病药物（如奥氮平）相关的NMS病例有所增加，但此类病例仍较少见。在此，我们报告一例双相情感障碍患者的NMS病例，该患者在过去7年中一直使用5毫克奥氮平进行维持治疗。他接受溴隐亭治疗成功，10天后病情稳定出院。
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