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纤维肌痛症患者的临床、心理特征和生活质量:中国样本的横断面研究。

Clinical, psychological features and quality of life of fibromyalgia patients: a cross-sectional study of Chinese sample.

机构信息

Department of Rheumatology, Chinese PLA General Hospital, No.28, FuXing Road, Beijing, 100853, China.

Department of Psychology, Chinese PLA General Hospital, Beijing, China.

出版信息

Clin Rheumatol. 2018 Feb;37(2):527-537. doi: 10.1007/s10067-017-3872-6. Epub 2017 Oct 13.

Abstract

This study aimed to determine the clinical, psychological features, and quality of life in Chinese fibromyalgia (FM) patients who fulfilled the American College of Rheumatology (ACR) 2010 FM classification criteria at initial diagnosis. A cross-sectional study was carried out in the Chinese People's Liberation Army (PLA) General Hospital. A hundred and seven Chinese FM patients (86 females, 21 males) were included. Eighty-six patients completed the questionnaires. Descriptive, differences, and correlation analyses were performed. The results showed that Chinese FM patients started their diseases at a median age of 37 years, with a male-to-female ratio of 1:4.1. Most patients were diagnosed about 2 years after symptoms onset. Nearly 60 % (59.81%) patients had less than college education, 58.88% did not have a full-time job, and 41.12% had low-back pain. Out of 86 patients, 58 (67.4%) had anxiety and 75 (87.2%) had depression. FM patients had poor quality of life in each aspect and deficient social support. The level of pain for the past 7 days was strongly correlated with patient global impression of severity (PGI-S; r = 0.651, p < 0.001) and patient global impression of bother (PGI-B; r = 0.628, p < 0.001). PGI-B was correlated with seven subscales of short-form health survey (SF-36). The study demonstrated the clinical, psychological features of Chinese patients. The diagnosis was delayed for about 2 years. Most of the patients had anxiety and depression, had poor quality of life, and lacked proper social support. PGI-B might be a simple measurement to evaluate patients' quality of life.

摘要

这项研究旨在确定符合美国风湿病学会(ACR)2010 年纤维肌痛(FM)分类标准的中国 FM 患者的临床、心理特征和生活质量。该研究采用横断面研究,在中国人民解放军总医院进行。共纳入 107 例中国 FM 患者(86 例女性,21 例男性),其中 86 例完成了问卷调查。进行了描述性、差异和相关性分析。结果显示,中国 FM 患者起病中位年龄为 37 岁,男女比例为 1:4.1。大多数患者在症状出现后约 2 年被诊断。近 60%(59.81%)的患者受教育程度低于大学,58.88%没有全职工作,41.12%有腰痛。在 86 例患者中,58 例(67.4%)有焦虑,75 例(87.2%)有抑郁。FM 患者在各方面的生活质量均较差,社会支持不足。过去 7 天的疼痛程度与患者总体印象严重程度(PGI-S;r=0.651,p<0.001)和患者总体印象困扰程度(PGI-B;r=0.628,p<0.001)呈强相关。PGI-B 与健康调查简表(SF-36)的七个子量表相关。该研究显示了中国患者的临床、心理特征。诊断延迟了约 2 年。大多数患者有焦虑和抑郁,生活质量较差,缺乏适当的社会支持。PGI-B 可能是评估患者生活质量的一种简单方法。

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