Department of Surgery "P. Valdoni", UOC of Plastic Surgery, "Sapienza" University of Rome, Policlinico Umberto I, Rome, Italy.
Eur Rev Med Pharmacol Sci. 2017 Sep;21(18):4124-4128.
The presence of ectopic or supernumerary breast tissue is a rare event, related to a not complete regression of breast tissue along the milk line. Primary ectopic breast cancer of the axilla can create many difficulties in differential diagnosis with subsequent delayed specific treatments. The incidence of ectopic breast tissue is 0.2-6%, and the axilla is the most common site involved. In this tissue, the same physiologic and pathologic changes as seen in ectopic breast tissue may occur, including carcinoma formation.
Two patients (a 56 years old and 70 years old women) came to our attention for the recent development painless nodular axillary lesions, clinically characterized by an increased thickness, irregular margins and adherence to the floors below.
Patients underwent ultrasonography (US) and mammography (MMG) revealing non-specific features of the lesions. Magnetic resonance imaging (MRI), demonstrated margins slightly irregular and a non-specific appearance of each lesion. Both patients underwent wide local excision with axillary lymph node dissection. Histological examination showed infiltrating lobular carcinomas of the breasts.
We describe two unusual cases of ectopic axillary breast carcinoma localization. It is important a correct and fast diagnosis with a local examination, diagnostic instruments, surgical excision and histological examination.
异位或多余的乳腺组织是一种罕见的现象，与沿乳腺线的乳腺组织不完全退化有关。原发性腋窝异位乳腺癌在鉴别诊断时会带来很多困难，进而导致后续的特异性治疗延误。异位乳腺组织的发生率为 0.2-6%，腋窝是最常见的受累部位。在该组织中，可能会发生与异位乳腺组织相同的生理和病理变化，包括癌形成。
两名患者（一名 56 岁和一名 70 岁的女性）因最近出现无痛性结节性腋窝病变而就诊，临床特征为厚度增加、边缘不规则且与下方组织粘连。
患者接受了超声（US）和乳房 X 线照相术（MMG）检查，显示病变无特异性。磁共振成像（MRI）显示边缘稍不规则，每个病变均呈非特异性外观。两名患者均接受了广泛的局部切除和腋窝淋巴结清扫。组织学检查显示乳腺浸润性小叶癌。
我们描述了两种不常见的异位腋窝乳腺癌定位的病例。正确快速的诊断需要进行局部检查、诊断仪器检查、手术切除和组织学检查。
