López-Soriano F J, Alemany M
Departament de Bioquímica i Fisiologia, Facultat de Biologia, Universitat de Barcelona, Spain.
Biochem Int. 1988 Jun;16(6):1075-81.
The activities of alanine, aspartate and branched-chain amino acid transaminases, glutamate dehydrogenase, glutamine synthetase and adenylate deaminase have been studied in liver of male rats exposed [12 hours at 4 degrees C] or acclimated [15 days at 4 degrees C] to cold temperature. Cold temperature induced an increase of the activities of glutamate dehydrogenase and alanine and aspartate transaminases both in cold-exposed and cold-acclimated animals; adenylate deaminase activity diminished after 15-day cold acclimation. There were not significant changes induced by cold temperature in the activities of the other two enzymes studied. These results agree with a possible direct implication of amino acid utilization by the liver in the context of the overall thermogenic response to cold temperature.
在暴露于低温[4℃，12小时]或适应低温[4℃，15天]的雄性大鼠肝脏中，对丙氨酸、天冬氨酸和支链氨基酸转氨酶、谷氨酸脱氢酶、谷氨酰胺合成酶和腺苷酸脱氨酶的活性进行了研究。低温导致暴露于寒冷和适应寒冷的动物体内谷氨酸脱氢酶以及丙氨酸和天冬氨酸转氨酶的活性增加；在15天的冷适应后，腺苷酸脱氨酶活性降低。低温对所研究的其他两种酶的活性没有显著影响。这些结果与肝脏对氨基酸的利用在对低温的整体产热反应中可能具有直接影响这一观点相符。
