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缺血性心肌病心内膜线性梗死排除技术的 10 年经验。

Ten-year experience of endocardial linear infarct exclusion technique for ischaemic cardiomyopathy.

机构信息

Department of Cardiovascular Surgery, Kyoto Prefectural University of Medicine, Kyoto, Japan.

出版信息

Eur J Cardiothorac Surg. 2018 Feb 1;53(2):440-447. doi: 10.1093/ejcts/ezx343.

Abstract

OBJECTIVES

To report the mid-term results of our surgical ventricular restoration procedure, called the endocardial linear infarct exclusion technique (ELIET), for ischaemic cardiomyopathy.

METHODS

From 2006 to 2015, 43 consecutive patients who underwent surgical ventricular restoration with ELIET for ischaemic cardiomyopathy were retrospectively analysed.

RESULTS

The mean age of patients at surgery was 65.3 ± 9.2 years and EuroSCORE II was 13.7 ± 12.0% (median 9.3%). The mean number of distal anastomoses of coronary artery bypass was 2.8 ± 1.5. A concomitant mitral procedure was performed in 58.1% of patients. The hospital mortality rate was 11.6% (5 patients). The ejection fraction was improved from 24.1 ± 9.2% to 31.7 ± 8.2% in 2 weeks after surgery. The end-systolic left ventricular volume index was effectively reduced, irrespective of performing a concomitant mitral procedure (reduction rate, ELIET: 35.6% vs ELIET + mitral: 39.2%). After ELIET, the sphericity index of the left ventricle did not worsen, and the conicity index was significantly improved. The 5-year estimated rates of survival and freedom from cardiac events were 71.3 ± 7.9 and 61.1 ± 8.3%, respectively. A concomitant mitral procedure was significantly associated with cardiac events based on univariate Cox hazard analysis.

CONCLUSIONS

This study showed that ELIET can effectively reduce the ventricular volume and create an ellipsoidal left ventricle.

摘要

目的

报告我们的心肌梗死后心室重构手术(即心内膜线性梗死排除技术,ELIET)治疗缺血性心肌病的中期结果。

方法

回顾性分析 2006 年至 2015 年间 43 例接受 ELIET 手术治疗缺血性心肌病的连续患者。

结果

手术时患者的平均年龄为 65.3±9.2 岁,EuroSCORE II 为 13.7±12.0%(中位数 9.3%)。冠状动脉旁路移植术的平均远端吻合口数为 2.8±1.5。58.1%的患者同时进行了二尖瓣手术。住院死亡率为 11.6%(5 例)。术后 2 周射血分数从 24.1±9.2%提高至 31.7±8.2%。左心室收缩末期容积指数有效降低,与是否同时进行二尖瓣手术无关(ELIET 组:35.6%,ELIET+二尖瓣组:39.2%)。ELIET 后,左心室的球形指数没有恶化,圆锥指数显著改善。ELIET 后 5 年生存率和无心脏事件生存率分别为 71.3±7.9%和 61.1±8.3%。单因素 Cox 风险分析显示,同时进行二尖瓣手术与心脏事件显著相关。

结论

本研究表明,ELIET 可有效减少心室容积并形成椭圆形左心室。

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